Thymolipoma with massive pleural effusion: A case report

Bayramoğlu, Zeynep; Ömeroğlu, Ethem; Ünlü, Yaşar

doi:10.28982/josam.507306

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…Тимоліпоми налічують приблизно 2-9% усіх новоутворень тимуса. У світовій літературі опубліковано менше 200 таких випадків, частота виникнення серед чоловіків і жінок однакова, патологія може розвиватись у будь-якому віці [1]. У деяких випадках ти моліпома може поєднуватися з хронічним лімфолейкозом, міастенією, апластичною анемією, гіпертиреозом і хворобою Ходжкіна [5].…”

Section: клінічний випадокunclassified

Clinical case report of gigantic thymolipoma in 3-year-old child

Krivchenya¹,

Rudenko²,

Metlenko³

et al. 2022

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Thymolipoma is a rare benign encapsulated tumor of anterior mediastinum. Overall, thymic neoplasms comprise only 4% of all mediastinal tumors. Only 2–9% of these are reported to be thymolipomas. Less than 200 cases have been published in the world literature and its incidence in both genders is equal and usually develops at any age. The youngest case in the literature was described in 6-month-old child. Thymolipoma can be associated with chronic lymphocytic leukemia, myasthenia graves, aplastic anemia, hyperthyroidism and Hodgkin’s disease. Half of the patients are asymptomatic, the neoplasm incidentally is discovered radiologically. The other half mostly represents shortness of breath, cough, chest pain and upper respiratory tract infection. The clinical case, diagnosis and treatment of gigantic thymolipoma in 3-year-old child is described in this article. A clinical case of giant thymolipoma in a 3-year-old child is presented. The child had several respiratory symptoms: episodes of choking, dry cough, groaning breathing during physical exertion and anxiety, chest deformity (enlarging the right half) and signs of type II respiratory failure. Radiographically - subtotal darkening of the right hemithorax with mediastinal shift to the contralateral side with compression of the left lung; laboratory results - hyperleukocytosis(39х109/l). Computed tomography showed a large hypovascular mass formation with inhomogeneous structure and areas of lipomatosis. Most likely, this is the case of congenital nature of thymolipoma, which manifested itself at the age of 3. Correct pathomorphological diagnosis was made with the help of open biopsy, since when performing the puncture method, there is a possibility of verification error due to insufficient amount of histological material given the inhomogeneity of the mass of the formation, as well as taking into account the suspicion of a lymphoproliferative process. Considering the mediastinal and intrathoracic compression syndrome, as well as the benign nature of these tumor, which is characterized by the absence of infiltrative growth, the only correct treatment tactic is radical surgery. The research was carried out in accordance with the principles of the Helsinki declaration. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: neoplasms of anterior mediastinum, thymolipoma, children.

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Section: клінічний випадокunclassified

Clinical case report of gigantic thymolipoma in 3-year-old child

Krivchenya¹,

Rudenko²,

Metlenko³

et al. 2022

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“…[3] Very rarely thymolipomas may contain carcinoid tumors and thymomas. [1] Differential diagnosis includes thymic hyperplasia, lipoma and liposarcoma of the mediastinum. [2] Lipoma will lack thymic epithelial tissue and liposarcoma will show higher degree of atypia and lipoblasts.…”

Section: Fig 3: a -Scattered Thymic Tissue Interspersed With Varyingmentioning

confidence: 99%

“…Thymolipomas are rare, slow-growing, benign anterior mediastinal neoplasms composed of an admixture of mature adipocytes and nonneoplastic thymic tissue. [1] Any age group can be affected [2] and accounts for 2-9% of all thymic neoplasms. [3] It is mostly an incidental finding that is diagnosed during a workup for other medical problems.…”

Section: Introductionmentioning

confidence: 99%

Case Report of An Unusual Mediastinal Mass - Thymolipoma

Raju

Sethi

Moothiringode

et al. 2020

Ann of Pathol and Lab Med

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Thymolipomas are rare, slow-growing, benign anterior mediastinal neoplasms which are very often detected incidentally. Here we present a case of a 47 year old female who presented with chest discomfort and radiology revealed an anterior mediastinal mass. Total thymectomy was done and histopathology showed features consistent with thymolipoma. Very few cases of thymolipomas have been reported in Indian and world literature.

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Extensive mediastinal thymolipoma mimicking pulmonary edema

Mohamud¹,

Ahmed²,

Ali³

2020

Journal of Surgical Case Reports

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Thymolipoma is a rare benign slow-growing encapsulated tumor of anterior mediastinum that accounts for 2–9% of all thymic neoplasms. About 30–50% of them are asymptomatic and found incidentally. Less than 200 cases have been published in the world literature so far. Here we report a case of thymolipoma of an adult female presented with progressive dyspnea, chest tightness and non-productive chough for 2-month duration. All blood investigations were normal. Radiological examinations suggested the presence of fat and soft tissue within the tumor without invading the neighboring structures. We concluded that the only curative treatment of thymolipoma is surgical excision. Unfortunately, the patient did not give consent despite telling her the outcomes if we do not do the surgical procedure, and a week later she passed away due to respiratory distress secondary to the mass effect of the tumor.

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Thymolipoma with massive pleural effusion: A case report

Cited by 3 publications

References 9 publications

Clinical case report of gigantic thymolipoma in 3-year-old child

Clinical case report of gigantic thymolipoma in 3-year-old child

Case Report of An Unusual Mediastinal Mass - Thymolipoma

Extensive mediastinal thymolipoma mimicking pulmonary edema

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