Abstract:Background
Establishing the diagnosis of Adult onset Still's disease is very challenging. Mostly it is still a diagnosis of exclusion. Along with IL-1, IL-6 and TNFα, IL-18 is one of the cytokines which seem to play a pivotal role in the pathogenesis of AOSD. It has been described as potential biomarker to support the diagnosis of AOSD. Regarding the importance of IL-18 as a marker for disease activity published data are so far conflicting.
Objectives
The aim of the study was to contribute to the understandi… Show more
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