Abstract:Thrombotic thrombocytopenic purpura (TTP), which is typically characterized by fever and central nervous system manifestations and hemolytic uremic syndrome (HUS), in which renal failure is a prominent feature are the most common thrombotic microangiopathies (TMAs). TTP is usually associated with a severe deficiency of ADAMTS13 [a metalloproteinase involved in the degradation of von Willebrand factor (vWF) multimers], causing excessive accumulation of ultra-large vWF multimers and platelet aggregation with org… Show more
“…[12] In addition, HUS can also be seen in cases with occult cancer. [3] However, this cannot lead to the conclusion that HUS will be more serious or more increased in prevalence in E. coli -infected cancerous patients.…”
“…[12] In addition, HUS can also be seen in cases with occult cancer. [3] However, this cannot lead to the conclusion that HUS will be more serious or more increased in prevalence in E. coli -infected cancerous patients.…”
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