Thrombotic and Cardiovascular Events and Treatment Patterns Among Patients Hospitalized with COVID-19 in Japan: An Analysis of a Nationwide Medical Claims Database

Terasaka, Naoki; Matsuo, Yukako; Kataoka, Hirohide; Miyata, Yasuhiko; Anazawa, Yoshio

doi:10.1007/s40119-022-00263-9

Cited by 1 publication

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“…This may have been because some ACS patients were worried about contracting COVID-19, and some patients with mild symptoms may have chosen to take medicine at home instead of going to the hospital. COVID-19 directly affects the development of thrombotic coronary obstruction and can lead to myocardial infarction through several mechanisms, such as inducing an inflammatory storm, a hypercoagulable state, or thrombosis, or through viral infiltration of myocardial cells or other immunologic mechanisms [ 13 , 14 , 15 , 16 , 17 ]. Previous clinical studies have demonstrated that ACS morbidity and mortality have significantly increased during the COVID-19 pandemic [ 5 , 6 , 18 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of COVID-19 Pandemic on Acute Coronary Syndrome Clinical Practice Patterns: Findings from a Multicenter Clinician Survey in China

Feng¹,

Zang²,

Zheng³

et al. 2022

Rev. Cardiovasc. Med.

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Background:The coronavirus disease 2019 (COVID-19) pandemic has severely affected healthcare systems around the world. This study aimed to investigate the perceptions of cardiologists regarding how the COVID-19 pandemic has affected the clinical practice patterns for acute coronary syndrome (ACS). Methods: A multicenter clinician survey was sent to 300 cardiologists working in 22 provinces in China. The survey collected demographic information and inquired about their perceptions of how the COVID-19 pandemic has affected ACS clinical practice patterns. Results: The survey was completed by 211 (70.3%) cardiologists, 82.5% of whom were employed in tertiary hospitals, and 52.1% reported more than 10 years of clinical cardiology practice. Most respondents observed a reduction in ACS inpatients and outpatients in their hospitals during the pandemic. Only 29.9% of the respondents had access to a dedicated catheter room for the treatment of COVID-19-positive ACS patients. Most respondents stated that the COVID-19 pandemic had varying degrees of effect on the treatment of acute ST-segment elevation myocardial infarction (STEMI), acute non-ST-segment elevation myocardial infarction (NSTEMI), and unstable angina. Compared with the assumed non-pandemic period, in the designed clinical questions, the selection of coronary interventional therapy for STEMI, NSTEMI, and unstable angina during the COVID-19 pandemic was significantly decreased (all p < 0.05), and the selection of pharmacotherapy was increased (all p < 0.05). The selection of fibrinolytic therapy for STEMI during the pandemic was higher than in the assumed non-pandemic period (p < 0.05). Conclusions:The COVID-19 pandemic has profoundly affected ACS clinical practice patterns. The use of invasive therapies significantly decreased during the pandemic period, whereas pharmacotherapy was more often prescribed by the cardiologists.

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