Thrombospondin-1 associated with carotid intima–media thickness among individuals with hypertension
Hsiu-Fen Lin,
Meng-Ni Wu,
Chien-Yuan Chen
et al.
Abstract:In vivo and in vitro studies have demonstrated that thrombospondin-1 (TSP-1) is involved in atherosclerotic pathogenesis. However, the role of TSP-1 in clinical atherosclerosis remains unknown. This cross-sectional study investigated the relationship between TSP-1 and carotid intima–media thickness (IMT) and examined whether it interacts with conventional cardiovascular risk factors. A total of 587 participants were enrolled from February 2018 to December 2021. TSP-1 was dichotomized based on median value. Car… Show more
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