Thrombosis in Acute Promyelocytic Leukemia: The Current Understanding
Nikica Sabljic,
Mirjana Mitrovic,
Nikola Pantic
et al.
Abstract:Despite enormous improvement in the management of patients with acute promyelocytic leukemia (APL), the distinctive coagulopathy observed at presentation in affected patients is often life-threatening. While hemorrhagic manifestations are well known and described in this setting, APL-related thromboses are underappreciated. Data regarding this complication are scarce showing variable incidence. Furthermore, risk factors for thrombosis are inconsistent and unreliable; so, differentiation of increased risk of he… Show more
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