Thrombolytic Therapy for Acute Left Atrial Thrombus Formation in One Patient With Heart Failure and Atrial Fibrillation

Lee, Cheng-Hung; Chen, Chun‐Chi; Chern, Ming-Shyan

doi:10.1253/circj.71.604

Cited by 22 publications

(15 citation statements)

References 13 publications

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“…Surgical treatment may be a good option for patients with a high embolic risk and in cases where thrombolytic therapy is expected to increase the risk. 10…”

Section: Discussionmentioning

confidence: 99%

Hypereosinophilic Cardiac Involvement Presenting With Left Ventricular Massive Thrombus and Cardioembolic Stroke: A Case Report

et al. 2018

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Introduction:It is well known that the tendency toward thrombosis is increased in cancer patients. The increase in cancer procoagulant and tissue factor levels, endothelial damage, and stasis due to compression are among the most accused causes of thrombosis in cancer patients. Hypereosinophilia is a rare condition that causes endothelial damage leading to thrombosis. Case Presentation: We present a 64-year-old male patient with cardiac involvement of hypereosinophilia which developed in the T-cell lymphoma ground resulting in a fatal cardioembolic stroke. Despite normal left ventricular (LV) contractions, almost half of the ventricular volume was full of thrombus in this case. Conclusion: Hypereosinophilia is a rare cause of thrombus formation in the left ventricle in patients with preserved ejection fraction. However, hypereosinophilic cardiac involvement can lead to rapid, progressive, life-threatening complications.

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“…Surgical treatment may be a good option for patients with a high embolic risk and in cases where thrombolytic therapy is expected to increase the risk. 10…”

Section: Discussionmentioning

confidence: 99%

Hypereosinophilic Cardiac Involvement Presenting With Left Ventricular Massive Thrombus and Cardioembolic Stroke: A Case Report

et al. 2018

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“…Surgical treatment of thrombus has been reported previously [14]. Empiric anticoagulation therapy with warfarin has been used for both atrial [3][4][5] and ventricular thrombus [6][7]. By contrast, there has been no report about the efficacy of dabigatran on acute preexisting intracardiac thrombi.…”

Section: Discussionmentioning

confidence: 99%

“…In practice, such a treatment involves the empiric use of warfarin [3][4][5][6][7]. However, it is unclear whether dabigatran has thrombolytic action on acute pre-existing intracardiac thrombus.…”

Section: Introductionmentioning

confidence: 99%

Resolution of a left ventricular thrombus by the thrombolytic action of dabigatran

Nagamoto¹,

Shiomi²,

Matsuura³

et al. 2013

Heart Vessels

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A 77-year-old man was referred to our cardiovascular department for detailed examination after abnormal electrocardiography findings were obtained during a preoperative cataract surgery workup. Ultrasound echocardiography (UCG) and computed tomography (CT) revealed evidence of previous myocardial infarction with anteroseptal akinesis and a left ventricular (LV) thrombus (14 × 12 mm). Dabigatran (220 mg/day) was prescribed as an outpatient treatment, and the disappearance of the LV thrombus was confirmed by UCG and CT 27 days after dabigatran initiation. No thromboembolism occurred between treatment initiation and thrombus resolution. Our results indicate that dabigatran has thrombolytic action on an acute pre-existing intracardiac thrombus.

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“…However, surgery is indicated in cases with an elevated risk for embolism or for large thrombi where thrombolysis will likely increase risk of embolism [2,7]. This particular patient fit both of those criteria, with a previous stroke and large, mobile thrombus, warranting surgical removal.…”

Section: Discussionmentioning

confidence: 99%

Idiopathic massive left ventricular thrombus in HIV patient

Homer

Sheen

Lee

2012

J Cardiothorac Surg

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Thrombolytic Therapy for Acute Left Atrial Thrombus Formation in One Patient With Heart Failure and Atrial Fibrillation

Cited by 22 publications

References 13 publications

Hypereosinophilic Cardiac Involvement Presenting With Left Ventricular Massive Thrombus and Cardioembolic Stroke: A Case Report

Hypereosinophilic Cardiac Involvement Presenting With Left Ventricular Massive Thrombus and Cardioembolic Stroke: A Case Report

Resolution of a left ventricular thrombus by the thrombolytic action of dabigatran

Idiopathic massive left ventricular thrombus in HIV patient

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