Thrombocytosis in Children

Schaefer, Beverly A.

doi:10.1007/978-3-030-49980-8_12

Cited by 1 publication

(3 citation statements)

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“…Clemens Stockklausner et al reported that the most common causes were infections (49.5%), postsplenectomy (7.8%), Kawasaki disease (6.4%), tissue damage (4.5%), blood diseases (3.7%), malignancies (3.7%), renal diseases (3.2%), chronic inflammation (1.8%), essential thrombocythemia (0.5%), and other causes (3.7%) 10 . In some other studies, the frequencies of infections in secondary thrombocytosis were 39, 53, 30, and 63%, respectively [11][12][13][14] . In our study, infections (37.9%) were also the most common cause of secondary thrombocytosis in accordance with the previously published studies.…”

Section: Discussionmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 99%

“…The incidence of thrombocytosis secondary to anemia was reported as 12.0, 3.7, and 8.5% in various studies [12][13][14] . Only iron deficiency anemia was found in 17.2 and 8.0% of the cases in two studies 8,13 . In our study, 16.4 and 5.0% of patients had iron deficiency anemia and hemolytic anemia, respectively, with a higher rate of secondary thrombocytosis when compared to previously published studies.…”

Section: Discussionmentioning

confidence: 99%

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Thrombocytosis in children

Babacan

Şenol

2023

Rev. Assoc. Med. Bras.

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SUMMARY OBJECTIVE: We aimed to investigate the frequency and causes of thrombocytosis in patients admitted to the Department of Pediatric Hematology and Oncology of Elazig Fethi Sekin City Hospital, Elazig, Turkey. METHODS: Between 2019 and 2021, the laboratory parameters of 2,500 patients admitted to the Hematology Department were studied. During this examination, 319 (12.76%) patients were found to have thrombocytosis. Demographic characteristics (age and gender), hematologic parameters (hemoglobin, white blood cells, and platelets), and ultimate diagnoses ot the cases were recorded from their files. RESULTS: Of these 319 patients with thrombocytosis, 197 (1.8%) were male and 122 (38.2%) were female, and the mean age was 72.0±69.0 (1–216) months. The median platelet count of the patients was 590.43±280.12/μL (450,000–750,000). The most common cause of secondary thrombocytosis was infection, accounting for 37.9% of all patients. Other common causes were sickle cell anemia (21%), iron deficiency anemia (15.4%), colloid tissue disease (6.6%), hemolytic anemia (5.0%), splenectomy (4.5%), and other causes (9.7%). CONCLUSION: In our study, infections were the most common cause of thrombocytosis. In addition to infections, sickle cell anemia and iron deficiency anemia should also be considered in the differential diagnosis of thrombocytosis.

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