Thrombocytopenia in patients with acute post-streptococcal glomerulonephritis

Kaplan, B.; Esseltine, Dixie Lee

doi:10.1016/s0022-3476(78)81224-4

Cited by 16 publications

(9 citation statements)

References 8 publications

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“…Because of the low haemoglobin and platelet count and especially the markedly reduced serum haptoglobin level, the first diagnosis made by the paediatrician was HUS. Kaplan and Esseltine [3] reported two paediatric patients with AGN who also had thrombocytopenia; renal biopsy was not performed in these children. Renal biopsy, however, was not compatible with this diagnosis, given the marked diffuse hypercellularity and the exudative aspect of the glomeruli, the absence of fibrin and the presence of immune complexes on either side of the basement membrane.…”

Section: Discussionmentioning

confidence: 99%

A boy with acute renal failure

1995

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Section: Discussionmentioning

confidence: 99%

A boy with acute renal failure

1995

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“…The simultaneous occurrence of HUS and APGN has rarely been reported in children [2,7,8,10,11,14,15]. Whether this relation is causal or accidental remains open to debate.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous occurrence of the haemolytic uraemic syndrome and acute post-infectious glomerulonephritis

Laube¹,

Sarkissian

Hailemariam

et al. 2001

European Journal of Pediatrics

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We report on two children, a 12-year-old boy and a 6-year-old girl, with simultaneous occurrence of clinical and laboratory features consistent with both diarrhoea-negative haemolytic uraemic syndrome (D-HUS) and acute post-infectious glomerulonephritis (APGN). Both presented with acute renal insufficiency, hypertension and oedema. Laboratory evaluation revealed micro-angiopathic anaemia with burr cells, thrombocytopenia, elevated lactic dehydrogenase and low complement C3. Urinalysis showed marked proteinuria and haematuria. Renal biopsy was characteristic of APGN, but not of HUS. The outcome was good in both children. Conclusion. The simultaneous occurrence of diarrhoea-negative haemolytic uraemic syndrome and acute post-infectious glomerulonephritis is rare. The outcome is generally good as is expected in the latter condition in contrast to the former.

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“…However, thrombocytopenia has been reported very rarely in the course of APSGN. According to our investigation association of thrombocytopenia and ITP has been identified in a limited number of cases in literature (4,(7)(8)(9)(10). We would like to present a 13 year old male subject in whom an association of APSGN and ITP was found and who required careful treatment and follow-up.…”

Section: Introductionmentioning

confidence: 84%

“…When we screened the literature, we found that association of APSGN and ITP has been reported in 6 cases before (4,(7)(8)(9)(10). While the age of these patients ranged between 4 and 9 years, our case was 13 years old.…”

Section: Discussionmentioning

confidence: 99%

Akut poststreptokoksik glomerülonefritli bir çocuk hastada idiyopatik trombositopenik purpura

Bal¹,

Yurtseven²,

Şahbudak³

et al. 2011

tpa

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I Id di io op pa at th hi ic c t th hr ro om mb bo oc cy yt to op pe en ni ic c p pu ur rp pu ur ra a i in n a a c ch hi il ld d w wi it th h a ac cu ut te e p po os st ts st tr re ep pt to oc co oc cc ca al l g gl lo om me er ru ul lo on ne ep ph hr ri it ti is s A Al lk ka an n B Ba al l, , A Al li i Y Yu ur rt ts se ev ve en n, , Z Zü üm mr rü üt t fi fia ah hb bu ud da ak k, , M Mu ur ra at t A An n› ›l l, , N Ne ej ja at t A Ak ks su u

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Thrombocytopenia in patients with acute post-streptococcal glomerulonephritis

Cited by 16 publications

References 8 publications

A boy with acute renal failure

A boy with acute renal failure

Simultaneous occurrence of the haemolytic uraemic syndrome and acute post-infectious glomerulonephritis

Akut poststreptokoksik glomerülonefritli bir çocuk hastada idiyopatik trombositopenik purpura

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