Threshold effect on whole-cell catalysis of extra hyperviscous biosystem by a sealed oxygen supply biotechnology
Xia Hua,
YaTing Hu,
Jian Han
et al.
Abstract:The end-product concentration and productivity are critical issues in
economic competition between biotechnological commercials and the
chemical engineering industry. The prominent contradiction between
high-titer products and the large-scale oxygen demand for aerobic
biocatalysis leads to hyperviscosity, mass transport bottleneck in
[dynamically changing](javascript:;) polyphase biosystems, and
severe foaming problems. In this study, an intensification strategy for
the whole-cell catalytic preparation of high… Show more
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