A feeding study was
carried out to investigate the kinetics in
cow milk of the 17 polychlorinated dibenzo-
p
-dioxins
and dibenzofurans (PCDD/Fs), the 12 dioxin-like polychlorinated biphenyls
(DL-PCBs), and the 6 non-dioxin-like PCBs (NDL-PCBs) regulated by
the European (EU) legislation. A fortified ration (ΣPCDD/Fs
and DL-PCBs: 24.68 ng TEQ/day/cow; ΣNDL-PCBs: 163.99 μg/day/cow)
was given to the animals for 49 days, followed by 42 days on clean
feed. EU maximum limit for TEQ
PCDD/F+DL-PCB
was
exceeded in milk after 1 week of exposure, while for ΣNDL-PCBs,
after 5 weeks. Milk compliance was restored after 1 week on clean
feed, but to return to the basal TEQ
PCDD/F+DL-PCB
it took 42 days. At the end of the study, ΣNDL-PCBs had not
yet reached the basal level. The carryover rate of ΣNDL-PCBs
was 25.4%, while the carryover rate of TEQ
PCDD/F+DL-PCB
was 36.9%. The latter was mainly affected by the 12 congeners contributing
most to the toxic equivalent (TEQ) level, explaining the fast overcome
of the maximum limit in milk.