Three-Year Clinical Outcomes and Quality of Life after Retromuscular Resorbable Mesh Repair Using Fibrin Glue

Abstract

entral hernias are common, with over 400,000 repairs performed annually. 1 Although many repair techniques, mesh implants, and fixation strategies have been described, hernia recurrence is still estimated to occur in 24 to 43 percent of cases. 2 Considering that every 1 percent reduction in ventral hernia repair achieved through reduced recurrence rates may result in annual savings of at least $32 million, 1 the need for cost-efficient, effective hernia repair becomes clear. With the advent of the Rives-Stoppa retromuscular technique, 3 the hernia community has made great strides in reducing recurrence rates and surgical-site occurrences. 4 Historically, mesh fixation in this plane requires

Automatic Evaluation for Bioengineering of Human Artificial Ovary: A Model for Fertility Preservation for Prepubertal Female Patients with a Malignant Tumor

“…Fibrin is a Food and Drug Administration-approved material for wound treatment. Accordingly, its safety and compatibility with humans have been well-established [ 43 , 44 , 45 , 46 ].…”

3D Lipogluing: Preliminary Results of a Novel Technique for Direct Three-dimensional Fat Grafting in Breast Reconstruction Surgery

“…The harvested fat is processed by filtration using a metal sieve and washed with normal saline. The adipose tissue graft is then "glued" in place using fibrin glue [21][22][23][24] (ARTISS Baxter, Deerfield, Ill.), [25][26][27][28][29][30][31][32] creating our 3D lipoglued graft to augment the subcutaneous thickness of the mastectomy flaps. [See Video 1 (online), which shows a 3D lipogluing technique in two-step breast reconstruction after mastectomy.…”

Discussion: Three-Year Clinical Outcomes and Quality of Life after Retromuscular Resorbable Mesh Repair Using Fibrin Glue

“…This period is notable because it examines outcomes after the poly-4-hydroxybutyrate mesh used resorbs, which, as the authors note, occurs over 12 to 18 months postoperatively. 1 The authors examine the effectiveness of these mesh fixation measures through both objective clinical outcomes and patient-reported outcome measures. Abdominal hernias have been shown to greatly impact a patient's quality of life and ability to perform activities of daily living.…”

“…I n this article, Morris et al provide valuable insight into the long-term surgical outcomes of fibrin glue fixation of resorbable mesh during abdominal hernia repair in comparison to suture fixation. 1 Suture fixation is frequently used as a baseline for comparison of newer fixation methods, and although it is the standard for repair strength, it is associated with postoperative pain. 2 The authors build on their prior study that examined the immediate postoperative outcomes between suture and fibrin glue mesh fixation methods, with an extended study inclusion period and an increased number of included subjects.…”

“…This period is notable because it examines outcomes after the poly-4-hydroxybutyrate mesh used resorbs, which, as the authors note, occurs over 12 to 18 months postoperatively. 1…”