Three-year canaloplasty outcomes for the treatment of open-angle glaucoma: European study results

Abstract

Canaloplasty demonstrated significant and sustained IOP reductions accompanied by an excellent short- and long-term safety profile in adult patients with open-angle glaucoma.

Trabeculectomy versus canaloplasty (TVC study) in the treatment of patients with open‐angle glaucoma: a prospective randomized clinical trial

“…An intracorneal haematoma is rare and can be removed by stab incision (Tetz et al 2013), partial-thickness paracentesis (Gismondi & Brusini 2011) or Nd: YAG laser Descemet membranotomy (Robert & Harasymowycz 2013). Perforation of the trabeculo-Descemet window during dissection is an intraoperative complication during canaloplasty, which occurs in <10% of all cases (Shingleton et al 2008;Lewis et al 2009;Grieshaber et al 2010;Ayyala et al 2011;Bull et al 2011;Arthur et al 2013;Tetz et al 2013). These data are in line with our observations of Descemet detachment (6.7%) and hyphaema rate (23.3%) following canaloplasty.…”

“…With regard to complications, hyphaema is a common event after canaloplasty and is suggested as a positive predictor of surgical success as it indicates permeability of the distended trabecular meshwork (Shingleton et al 2008;Lewis et al 2009;Grieshaber et al 2010Grieshaber et al , 2013Ayyala et al 2011;Bull et al 2011;Arthur et al 2013;Matlach et al 2013;Tetz et al 2013). An intracorneal haematoma is rare and can be removed by stab incision (Tetz et al 2013), partial-thickness paracentesis (Gismondi & Brusini 2011) or Nd: YAG laser Descemet membranotomy (Robert & Harasymowycz 2013).…”

“…In line with our results, Ayyala et al (2011) observed a more pronounced IOP reduction after 12 months with fewer medications in trabeculectomy (mean 43%) than canaloplasty (mean 32%). Canaloplasty had a better IOP reduction when performed in combination with cataract surgery (Lewis et al 2007(Lewis et al , 2011Shingleton et al 2008;Bull et al 2011;Arthur et al 2013;Tetz et al 2013). …”

“…Previous studies comparing non-penetrating with penetrating glaucoma surgeries have reported that although canaloplasty may not be as effective as filtering surgery in lowering IOP without medication, complication rate and risk of serious vision-threatening adverse events are low (Ayyala et al 2011;Brusini & Tosoni 2012;Bruggemann et al 2013;Matlach et al 2013). In addition, the combination of canaloplasty with cataract surgery provides a better IOP reduction than single canaloplasty (Lewis et al 2007(Lewis et al , 2011Shingleton et al 2008;Bull et al 2011;Arthur et al 2013;Tetz et al 2013).…”

Modified 360-degree suture trabeculotomy combined with phacoemulsification and intraocular lens implantation for glaucoma and coexisting cataract

“…Non-filtering anti-glaucoma procedures such as trabeculotomy 8 and canaloplasty, 17 in which a bleb is not produced, could be more effective when combined with cataract surgery than those done alone. The original version of the 360-degree suture trabeculotomy is an advanced technique that opens the entire circumference of Schlemm's canal during a single surgical procedure, 9 unlike a trabeculotomy with metal trabeculotomes where the incision of Schlemm's canal is only 120 degrees.…”