Three unusual carcinoid tumours, with particular reference to osteoblastic bone metastases

Thomas, Blessy Mary

doi:10.1016/s0009-9260(68)80066-2

Cited by 26 publications

(3 citation statements)

References 18 publications

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“…There have been only about 20 cases illustrated radiographically and a few more described pathologically [13, 14, 33, [47][48][49][50]. There have been only about 20 cases illustrated radiographically and a few more described pathologically [13, 14, 33, [47][48][49][50].…”

Section: Carcinoids and Bony Metastasesmentioning

confidence: 99%

Carcinoid tumors of the alimentary tract

Balthazar

1978

Gastrointest Radiol

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This paper is based on a retrospective analysis of the radiographic findings in 18 new proven cases of carcinoids of the gastrointestinal tract. Examples of lesions involving different segments together with a detailed review of the pertinent literature are provided. Background information regarding the malignant potential of all carcinoids with particular reference to invasiveness, size, site, and symptomatology is discussed. Depending on the time of the examination during their development, carcinoids present either as smoothly defined, mostly small intramural nodules, or as large infiltrating and ulcerating malignant looking tumors. When mesenteric infiltration is present, a more specific combination of findings composed of submucosal nodules, separation of loops, and localized kinking may be seen. The demonstration of an isolated, sharply contoured defect does not exclude malignancy. The less common radiographic manifestations of tumoral calcifications and bony metastases are reviewed and illustrated.

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Section: Carcinoids and Bony Metastasesmentioning

confidence: 99%

Carcinoid tumors of the alimentary tract

Balthazar

1978

Gastrointest Radiol

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“…Despite the fact, that most bone lesions appear osteoblastic, formation markers are not elevated. 36,37 Neuroendocrine tumours are slowly growing, thus bone metastases may have an only marginal impact on the metabolism of the surrounding normal bone. Hence, the concentration of bone markers is not significantly changed in the presence of bone metastases.…”

Section: Bone Metastasesmentioning

confidence: 99%

Management of metastatic endocrine tumours

Plöckinger

Wiedenmann

2005

Best Practice & Research Clinical Gastroenterology

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“…ography (CT) of the abdomen and visceral angiography. Less usual sites of metastasis include bone, lung, subcu-In one patient a mass was noted at the time of cholecystaneous tissue, brain, testis, breast, and the neck [17][18][19][20][21][22][23][24][25][26]. tectomy and led to direct biopsy and diagnosis.…”

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confidence: 99%

Cervical metastases from small bowel carcinoid tumors

Marks

Strodel

Lloyd

et al. 1983

Journal of Surgical Oncology

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Small bowel carcinoid tumors usually metastasize to regional lymph nodes and the liver but metastases to the neck are extremely rare. Over a ten-year period 48 cases of small bowel carcinoid were diagnosed at our institution and of these, three cases (6%) were associated with neck metastases--one to the thyroid gland and two to cervical lymph nodes. The former patient and one of the latter patients had symptoms of the carcinoid syndrome. The other patient was asymptomatic and presented with a solitary neck mass. Urine levels of 5-hydroxyindolacetic acid (5-HIAA) were elevated in the two symptomatic patients but were undetectable in the asymptomatic patient. Extirpation of the involved cervical nodes and the primary small bowel lesion was performed in two patients. In addition, both patients have received chemotherapy with 5-fluorouracil. One patient remains asymptomatic four years after diagnosis but the other patient continues to have five to six bowel movements per day nine months after operation. Small bowel resection was performed in the patient with a metastasis to the thyroid. This patient died of sepsis after a second operation for an intraabdominal abscess. The histological patterns of the primary tumor and the metastatic lesions were similar and the cells of the metastases contained argentaffin-positive granules. We conclude that 1) an intraabdominal carcinoid tumor should be considered as the location of the primary tumor in patients who present with a neck mass containing metastatic carcinoid and 2) the prognosis for patients with extraabdominal metastases is similar to that for patients with intraabdominal disease only.

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Three unusual carcinoid tumours, with particular reference to osteoblastic bone metastases

Cited by 26 publications

References 18 publications

Carcinoid tumors of the alimentary tract

Carcinoid tumors of the alimentary tract

Management of metastatic endocrine tumours

Cervical metastases from small bowel carcinoid tumors

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