Three presentations of CNS disease in patients with intraocular retinoblastoma at a tertiary medical center in the United States

Abstract

Although rare in developed countries, patients with intraocular retinoblastoma can present with a spectrum of CNS findings at the time of diagnosis. Magnetic resonance imaging of the brain and orbits is a critical component of the staging evaluation.

Screening for Pineal Trilateral Retinoblastoma Revisited

“…Six articles [16][17][18][19][20][21] did not provide the age at diagnosis of trilateral retinoblastoma, two 22,23 reported on patients with a trilateral retinoblastoma but without an intraocular tumor, and three [24][25][26] did not report on patients with trilateral retinoblastoma at all and were excluded. The six remaining articles [27][28][29][30][31][32] provided fifteen new patients. Together with 174 patients from our earlier systematic review, 4 we compiled data from 189 patients with trilateral retinoblastoma (Appendix C).…”