Three-Phase Abdominal Scintigraphy in Lupus Vasculitis of the Gastrointestinal Tract

Wang, Shyh-Jen; Lan, Jung-Liang; Lin, Wan‐Yu; Liu, Ren-Shyan; Yeh, Su‐Ling

doi:10.1097/00003072-199508000-00007

Cited by 8 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Common CT scan findings in abdominal vasculitis include dilated bowel, focal or diffuse bowel wall thickening, abnormal bowel wall enhancement (double halo or target sign), mesenteric edema, engorged mesenteric vessel, and ascites (1,11). Although the findings of abdominal CT scans are suggestive of gastrointestinal vasculitis in 75% of patients with intestinal SLE, some patients with SLE without gastrointestinal symptoms also have similar findings (11,12). The major differentiation from thromboembolic disease in our patients was the prominent involvement of duodenum and territory supplied by the superior mesenteric vessel, consistent with a previous report (13).…”

Section: Discussionmentioning

confidence: 99%

Mesenteric Vasculitis as the Initial Presentation in Children With Systemic Lupus Erythematosus

Chen²,

Ou³

et al. 2009

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Mesenteric Vasculitis as the Initial Presentation in Children With Systemic Lupus Erythematosus

Chen²,

Ou³

et al. 2009

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

“…Gastrointestinal symptoms in patients with proven SLE are well recognized, and occur in approximately 30% of patients. Among all patients with gastrointestinal symptoms, 75% show signs of vasculitis (2). The sever-ity of clinical presentation of gastrointestinal SLE can vary from moderate gastroenteritis to severe abdominal pain, which can mimic an acute abdomen.…”

Section: Discussionmentioning

confidence: 99%

“…Abdominal Computed Tomography scans can only highlight generic signs such as dilated intestinal loops, thickening of the intestinal wall, and ascites. Scintigraphy with technetium‐99m is suggestive of gastrointestinal vasculitis in 75% of patients with intestinal SLE but it is not clinically very helpful in that 13% of SLE patients without gastrointestinal symptoms will have the same findings (2). The two patients presented here have had an unremarkable medical history until the onset of acute abdominal symptoms.…”

Section: Discussionmentioning

confidence: 99%

Acute Abdomen: the Presenting Sign of Systemic Lupus Erythematosus in Childhood

Lepore,

Facchini,

Codrich

et al. 2002

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

“…19 Three-phase abdominal Tc-99 m pyrophosphate scintigraphy may help to identify areas of vasculitis. 20 Mesenteric angiography is useful in excluding polyarteritis nodosa and may show diffuse irregularities of the small arteries in the intestine. 21 A negative examination does not exclude disease as vasculitis in SLE generally involves small arteries.…”

Section: Vasculitismentioning

confidence: 99%

Gastrointestinal and Hepatic Manifestations of Systemic Lupus Erythematosus

Ebert

Hagspiel

2011

Journal of Clinical Gastroenterology

135

View full text Add to dashboard Cite

In this review of the gastrointestinal (GI) and hepatic manifestations of systemic lupus erythematosus (SLE), 180 articles from the English literature, found using a medline search from January 1965 to December 2010, were examined. Vasculitis may cause ulcerations, bleeding, stricture formation, and perforation from ischemia and infarction. Otherwise, GI symptoms, occurring in about 50% of patients, are usually mild. Esophageal dysmotility may result in heartburn, regurgitation, and dysphagia. Occasionally, pneumatosis cystoides intestinalis may develop, sometimes associated with benign pneumoperitoneum. Patients are prone to salmonella bacteremia, presenting more commonly with fever and abdominal pain than with diarrhea. Intestinal pseudoobstruction usually is found with active lupus serology, preferentially involving small rather than the large bowel. Protein-losing enteropathy, characterized by diarrhea, edema, and hypoalbuminemia, can be the initial presentation of SLE. Malabsorption with a prevalence of 9.5% is occasionally associated with celiac disease. Pancreatitis, with an annual incidence of 0.4 to 1/1000, has an overall mortality of 27% that is decreased with corticosteroid therapy. Acute and chronic ascites may be due to lupus peritonitis or to associated diseases, such as pancreatitis, nephrotic syndrome, heart failure, or infections. Abnormal liver function tests may be due to steatosis from lupus or from corticosteroid therapy. Only about 10% of patients with autoimmune hepatitis have lupus. Up to 4.7% of patients with SLE have chronic active hepatitis correlating strongly with the presence of antibody to ribosomal P protein. SLE can involve the entire GI tract and the liver. Treatment with corticosteroids, cytotoxic agents, and/or immunosuppressants is often successful.

show abstract

Three-Phase Abdominal Scintigraphy in Lupus Vasculitis of the Gastrointestinal Tract

Cited by 8 publications

References 0 publications

Mesenteric Vasculitis as the Initial Presentation in Children With Systemic Lupus Erythematosus

Mesenteric Vasculitis as the Initial Presentation in Children With Systemic Lupus Erythematosus

Acute Abdomen: the Presenting Sign of Systemic Lupus Erythematosus in Childhood

Gastrointestinal and Hepatic Manifestations of Systemic Lupus Erythematosus

Contact Info

Product

Resources

About