Three new neolignan glucosides from the stems of Dendrobium aurantiacum var. denneanum

Li, Xiaohong; Guo, Li; Yang, Lian; Peng, Cheng; He, Chengjun; Zhou, Qin‐Mei; Xiong, Liang; Liu, Juan; Tingmo, Zhang

doi:10.1016/j.phytol.2014.03.013

Cited by 7 publications

(2 citation statements)

References 13 publications

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“…Combined with the spectrum type, it was suggested that the aglycone of the compound corresponding to these two peaks was one less hydroxyl than those corresponding to peaks 12, 13, 21 and 22. Furthermore, the base peak m / z 209 ion in the MS 3 analysis and m / z 194 ion in the MS 4 analysis indicated that the aglycone of the compound corresponding to peaks 31 and 32 was composed of two of sinapyl alcohols, which have previously been found in other Dendrobium species 28,29 . The fragment ion at m / z 401 [M−H−162−18] − corresponding to the loss of water was not detected, indicating that the glucoside was not attached to 9′‐O.…”

Section: Resultsmentioning

confidence: 78%

“…Furthermore, the base peak m/z 209 ion in the MS 3 analysis and m/z 194 ion in the MS 4 analysis indicated that the aglycone of the compound corresponding to peaks 31 and 32 was composed of two of sinapyl alcohols, which have previously been found in other Dendrobium species. 28,29 The fragment ion at m/z 401 [MÀHÀ162À18] À corresponding to the loss of water was not detected, indicating that the glucoside was not attached to 9 0 -O.…”

Section: Aryl Tetrahydronaphthalene Lignansmentioning

confidence: 99%

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Identification of lignans and quality assessment in Dendrobium officinale under different cultivation modes

Zhang

et al. 2023

Rapid Comm Mass Spectrometry

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Rationale Lignans have attracted much attention from researchers because of their wide distribution and industrial applications in plants, as well as the remarkable diversity of their biological activities. As the literature has mainly focused on the extraction and identification of monomeric compounds of lignans, most lignans in Dendrobium officinale, a traditional Chinese medicine with a long cultivation history and rich sources, have not been detected using quality control methods. The aim of this study was to identify the lignans in Dactilon officinale. Methods High‐performance liquid chromatography (HPLC) coupled with diode array detection and HPLC multiple‐stage tandem mass spectrometry was used to identify the chemical constituents of D. officinale. Simultaneously, the characteristic chromatograms of D. officinale were established. Additionally, a method was established to determine the content of syringaresinol‐4,4′‐di‐O‐β‐D‐glucoside, syringaresinol‐4‐O‐β‐D‐glucoside and syringaresinol. Results Thirty‐three lignans, including 17 tetrahydrofuran lignans, two dibenzylbutane lignans, three aryl tetrahydronaphthalene lignans and 11 8‐O‐4′‐neolignans, were tentatively identified from the methanol extract of the stems of D. officinale. This is the first report of 8‐O‐4′‐neolignans from D. officinale. In addition, a total of eight characteristic peaks were marked in characteristic chromatograms, which were identified as lyoniresinol‐9′‐O‐β‐D‐glucoside, syringaresinol‐4,4′‐di‐O‐β‐D‐glucoside, 8‐hydroxy‐syringaresinol‐4‐O‐β‐D‐glucoside, 5,5′‐dimethoxy‐lariciresinol‐4‐O‐β‐D‐glucoside, syringaresinol‐4‐O‐β‐D‐glucoside, 4‐hydroxy‐3,3′,5,5′‐tetramethoxy‐8,4′‐oxyneoligna‐7′‐ene‐9,9′‐diol‐9‐O‐β‐D‐glucoside, 4‐hydroxy‐3,3′,5,5′‐tetramethoxy‐8,4′‐oxyneoligna‐7′‐ene‐9,9′‐diol‐4‐O‐β‐D‐glucoside and syringaresinol. Our results showed that no significant difference occurred in lignan composition among the 99 batches of D. officinale from different sources. However, the peak areas of the lignans of D. officinale planted under simulated wild culture were generally higher than those in greenhouses, and showed an upward trend with the increase in growth years. The average contents of syringaresinol‐4,4′‐di‐O‐β‐D‐glucoside, syringaresinol‐4‐O‐β‐D‐glucoside and syringaresinol were 10.112–179.873, 51.227–222.294 and 6.368–120.341 μg/g, respectively. Conclusions This study provided a basis for improving the quality control of D. officinale and could provide references for the identification of lignans in other Dendrobium species.

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Section: Resultsmentioning

confidence: 78%