Three New Compounds from Aspergillus terreus PT06-2 Grown in a High Salt Medium

Wang, Yi; Zheng, Jinkai; Li, Peipei; Wang, Wei; Zhu, Weiming

doi:10.3390/md9081368

Cited by 108 publications

(61 citation statements)

References 32 publications

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“…A study carried out by Kumar et al (2000) showed the production of an inhibition zone by A. terreus against Neurospora crassa . Moreover, a study by Wang et al (2011) revealed that new compounds from A. terreus could produce inhibition zone against Pseudomonas aeruginosa and Enterobacter aerogenes growth. It is likely that an inhibition zone was produced because A. terreus secrets metabolites that interfere with the growth of P. aphanidermatum .…”

Section: Discussionmentioning

confidence: 99%

“…It is likely that an inhibition zone was produced because A. terreus secrets metabolites that interfere with the growth of P. aphanidermatum . Ferrón et al (2005) and Wang et al (2011) reported the production of terremides A and B and lovastatin by A. terreus that were found responsible for the production of inhibition zones. In our study, the use of CF from A. terreus isolates resulted in electrolyte leakage in P. aphanidermatum mycelium and also interfered with oospore production in P. aphanidermatum .…”

Section: Discussionmentioning

confidence: 99%

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Aspergillus terreus Inhibits Growth and Induces Morphological Abnormalities in Pythium aphanidermatum and Suppresses Pythium-Induced Damping-Off of Cucumber

2018

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The study investigated the efficacy of two isolates of Aspergillus terreus (65P and 9F) on the growth, morphology and pathogenicity of Pythium aphanidermatum on cucumber. In vitro tests showed that the two isolates inhibited the growth of P. aphanidermatum in culture. Investigating P. aphanidermatum hyphae close to the inhibition zone showed that the hyphae showed abnormal growth and loss of internal content. Treating P. aphanidermatum with the culture filtrate (CF) of A. terreus resulted in significant rise in cellular leakage of P. aphanidermatum mycelium. Testing glucanase enzyme activity by both A. terreus isolates showed a significant increase in glucanase activity. This suggests that the cell walls of Pythium, which consist of glucan, are affected by the glucanase enzyme produced by A. terreus. In addition, Aspergillus isolates produced siderephore, which is suggested to be involved in inhibition of Pythium growth. Also, the CFs of 65P and 9F isolates significantly reduced spore production by P. aphanidermatum compared to the control (P < 0.05). In bioassay tests, the two isolates of A. terreus increased the survival rate of cucumber seedlings from 10 to 20% in the control seedlings treated with P. aphanidermatum to 38–39% when the biocontrol agents were used. No disease symptoms were observed on cucumber seedlings only treated with the isolates 65P and 9F of A. terreus. In addition, the A. terreus isolates did not have any negative effects on the growth of cucumber seedlings. This study shows that isolates of A. terreus can help suppress Pythium-induced damping-off of cucumber, which is suggested to be through the effect of A. terreus and its glucanase enzyme on P. aphanidermatum mycelium.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Aspergillus terreus Inhibits Growth and Induces Morphological Abnormalities in Pythium aphanidermatum and Suppresses Pythium-Induced Damping-Off of Cucumber

2018

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“…[1][2][3] Butyrolactones were mainly found as metabolites from fungi and high plants in nature. 4 They appeal to medicinal chemists because of their pronounced pharmacological effects including antibacterial, 5,6 anti-tumor, 7,8 anti-inflammatory, 9,10 anti-virus, 11,12 and the like.…”

Section: Introductionmentioning

confidence: 99%

Butyrolactones Derivatives from the Fermentation Products of an Endophytic Fungus Aspergillus versicolor

Ye¹,

Xia²,

Yang³

et al. 2014

Bulletin of the Korean Chemical Society

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Two new butyrolactones, asperphenol A (1) and B (2), together with four known butyrolactones (3-6) were isolated from the fermentation products of an endophytic fungus Aspergillus versicolor. Their structures were elucidated by spectroscopic methods including extensive 1D-and 2D-NMR techniques. Compounds 1-6 were also tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compound 2 exhibited high anti-TMV activity with inhibition rate of 46.7%. The other compounds also exhibited potential anti-TMV activities with inhibition rates in the range of 21.8-28.4%.

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“…This compound is produced by the strain Aspergillus terreus [9] and is reported to have antimicrobial, cytotoxic, nematicidal, and phytotoxic activities [10].…”

Section: R(-)-6-hydroxymellein (3) Colorless Solid Crystal (Etoac Mmentioning

confidence: 99%

Secondary Metabolites Isolated from the Strain Aspergillus terreus

et al. 2014

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Three New Compounds from Aspergillus terreus PT06-2 Grown in a High Salt Medium

Cited by 108 publications

References 32 publications

Aspergillus terreus Inhibits Growth and Induces Morphological Abnormalities in Pythium aphanidermatum and Suppresses Pythium-Induced Damping-Off of Cucumber

Aspergillus terreus Inhibits Growth and Induces Morphological Abnormalities in Pythium aphanidermatum and Suppresses Pythium-Induced Damping-Off of Cucumber

Butyrolactones Derivatives from the Fermentation Products of an Endophytic Fungus Aspergillus versicolor

Secondary Metabolites Isolated from the Strain Aspergillus terreus

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