Three-Input Logic AND Gate Drives Sequential Three-Step Catalysis by Parallel Activation of H⁺ and Ag⁺ as a Catalyst Duo

Abstract

Boolean operations with multiple catalysts as output are yet unknown using molecular logic. The issue is solved using a two-component ensemble, composed of a receptor and rotaxane, which acts as a three-input AND gate with a dual catalytic output. Actuation of the ensemble gate by the stoichiometric addition of metal ions (Ag+ and Cd2+) and 2,2,2-trifluoroacetic acid generated in the (1,1,1) truth table state a catalyst duo that synergistically enabled a three-step reaction, furnishing a dihydroisoquinoline as the output of a three-input logic AND gate operation.

A Constitutionally Dynamic Cage Acts as a Convertible and Adaptable Information Manager in Supramolecular Logic

“…As a second receptor, we chose [2]rotaxane 2 , which is known to form the bis‐stable mechanically interlocked complex [Cu( 2 )] + with a high shuttling dynamics ( k 298 =30 kHz) [27] . Additionally, [2]rotaxane 2 may serve as a proton binder owing to the enhanced basicity that emerges from the cooperative H + stabilization in the mechanically interlocked structure [15] . Further, use of the luminophore 3 with its pH‐dependent emission properties [28] should offer access to optical read‐out when the appropriate stimulus is applied.…”

Designing Next‐Generation Molecular Logic Circuits: Photonic Concatenation in Upconverting Nanocrystals

“…One of the dammed challenges in molecular logic is concatenation, in which the output of a first gate is the input of the following one. Some examples of chemical and biochemical concatenation have been reported so far exploiting enzymatic systems, [17,18] fluorescent boronic acid sugar probes, [19] DNA molecules, [20] and other molecular species. [21] In general, the concatenation demands input-output homogeneity, and its implementation at the molecular scale is commonly limiting the integration of these molecular equivalents in hybrid molecularelectronic circuits and the development of full molecular logic circuits.…”

Self-Healing of a Copper(I) [2]Rotaxane Shuttle Monitored by Fluorescence

“…Building on the reversibility of the required complexation, we chose the known [2]­rotaxane R (Figure ), equipped with the pyridine macrocycle 1 , for further interrogation. Upon addition of copper­(I), [Cu­( R )] + was afforded that , according to literature, showed a fast-shuttling motion along the thread between the two degenerate triazole stations ( k 298 = 3.0 × 10 4 Hz)…”