Three Heterocyclic Rings Fused (5-6-6)

Hypoiodite-Catalyzed Chemoselective Tandem Oxidation of Homotryptamines to Peroxy- and Epoxytetrahydropyridoindolenines

“…Indole alkaloids constitute one of the largest groups of nitrogen-containing secondary metabolites, and more than 4000 indole alkaloids have already been found in nature . Because of their significant and wide range of biological activities, the development of efficient methods for the synthesis of indole alkaloids is one of the most important topics in synthetic organic chemistry, especially for drug discovery. , Beside indole, the most common structural motifs found in various indole-derived alkaloids are indolenine, indoline, and oxindole . Oxidative dearomative functionalization of indoles is one of the most important strategies for construction of these structures .…”