1984
DOI: 10.1016/s0338-4535(84)80083-5
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Three examples of anti-Fy3 produced in negroes

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Cited by 8 publications
(9 citation statements)
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“…This arises from homozygosity for FY*B allele carrying a c.1-67T>C in the GATA-1 box promoter region (FY*02N.01) preventing Fy b expression on red blood cells (RBC) [14,18]. However, the Duffy antigens are expressed in non-erythroid tissues, and Africans with the Fy(a-b-) phenotype rarely make anti-Fy b or anti-Fy3 [2, [19][20][21][22][23][24].…”
Section: Introductionmentioning
confidence: 99%
“…This arises from homozygosity for FY*B allele carrying a c.1-67T>C in the GATA-1 box promoter region (FY*02N.01) preventing Fy b expression on red blood cells (RBC) [14,18]. However, the Duffy antigens are expressed in non-erythroid tissues, and Africans with the Fy(a-b-) phenotype rarely make anti-Fy b or anti-Fy3 [2, [19][20][21][22][23][24].…”
Section: Introductionmentioning
confidence: 99%
“…Since that initial report, several other examples of anti-Fy3 have been described. [16][17][18][19][20][21][22] This is a clinically significant antibody associated with mild HDN in two offspring of the initially reported subjects. 15,16 Additional cases of this antibody developing after transfusion have been cited.…”
Section: Discussionmentioning
confidence: 94%
“…African American patients who developed anti-Fy3, with or without signs and symptoms of hemolysis, usually had concomitant alloantibodies within the Duffy system, especially anti-Fy a . 19,20,23 We are describing a patient who developed an intravascular hemolysis due to anti-Fy3, in the absence of any other alloantibody. This patient had a history of RBC transfusion.…”
Section: Discussionmentioning
confidence: 99%
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“…Fy b is expressed on other tissues. These patients remain at risk for anti-Fy3, which can be clinically significant, and patients with an existing anti-Fy a are at increased risk (9,13). The reasons for this have long been studied but are yet to be determined.…”
mentioning
confidence: 99%