Three-dimensional printing
            <i>in vitro</i>
            simulation of percutaneous pulmonary valve implantation in large right ventricular outflow tract

Valverde, Israel; Sarnago, Fernando; Prieto, Raquel; Zunzunegui, José Luis

doi:10.1093/eurheartj/ehw546

Cited by 11 publications

(17 citation statements)

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“…However, the density of trabeculations and irregularities, combined with dilatation of the right ventricle of these patients, often make it difficult to perform the percutaneous implantation of the valve, leading to prolonged procedure and radiation times. Several studies have aimed to plan the valve implantation using patientspecific models, 51 based on segmentations from MRI 52 and CT. 53 In these studies, 3D models helped the whole multidisciplinary team to visualise the intervention, try out different strategies, and design individualised solutions for a population with widely differing cardiac anatomies 53 and more accurate selection of patients for percutaneous pulmonary valve implantation than using MRI images alone, 52 as well as better planning of the procedure in the context of complications like right ventricular outflow tract aneurysms. 54 Education and training 3D printing models have the potential to serve as unique educational tools for healthcare professionals.…”

Section: Clinical Practicementioning

confidence: 99%

“…Patient-specific 3D-printed models have extensively proven to have a significant effect in clinical decision making and procedure planning in open-heart surgery or cardiac catheterisation, allowing for development of new techniques and approaches in patients with CHD. [33][34][35][37][38][39]41,47,9,10,16,20,[48][49][50][51][52] Special efforts are currently being made in order to improve the materials that the models are built with in order to mimic the behaviour of the myocardium, the valve leaflets, and the great vessels' wall as much as possible. Differences in healthy and pathologic cardiac tissue are also to be taken into account.…”

Section: Limitations and Future Directionsmentioning

confidence: 99%

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Living the heart in three dimensions: applications of 3D printing in CHD

et al. 2019

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Advances in biomedical engineering have led to three-dimensional (3D)-printed models being used for a broad range of different applications. Teaching medical personnel, communicating with patients and relatives, planning complex heart surgery, or designing new techniques for repair of CHD via cardiac catheterisation are now options available using patient-specific 3D-printed models. The management of CHD can be challenging owing to the wide spectrum of morphological conditions and the differences between patients. Direct visualisation and manipulation of the patients’ individual anatomy has opened new horizons in personalised treatment, providing the possibility of performing the whole procedure in vitro beforehand, thus anticipating complications and possible outcomes. In this review, we discuss the workflow to implement 3D printing in clinical practice, the imaging modalities used for anatomical segmentation, the applications of this emerging technique in patients with structural heart disease, and its limitations and future directions.

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Section: Clinical Practicementioning

confidence: 99%

Section: Limitations and Future Directionsmentioning

confidence: 99%

Living the heart in three dimensions: applications of 3D printing in CHD

et al. 2019

Self Cite

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“…Three-dimensional printed models may aid in patient education [ 99 ]. In vitro simulation with 3D models might help planning PPVI in native RVOTs [ 100 ].…”

Section: Advanced Imagingmentioning

confidence: 99%

“…A double stent technique was reported by Valverde et al . [ 99 ]. A 3D print was used to test double stent implantation in a 36 mm RVOT.…”

Section: Decellurarized Human Valvesmentioning

confidence: 99%

Percutaneous Pulmonary Valve Implantation: Current Status and Future Perspectives

Driesen

Warmerdam

Sieswerda

et al. 2019

CCR

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Patients with congenital heart disease (CHD) with right ventricle outflow tract (RVOT) dysfunction need sequential pulmonary valve replacements throughout their life in the majority of cases. Since their introduction in 2000, the number of percutaneous pulmonary valve implantations (PPVI) has grown and reached over 10,000 procedures worldwide. Overall, PPVI has been proven safe and effective, but some anatomical variations can limit procedural success. This review discusses the current status and future perspectives of the procedure.

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“…17,74,75 Three-dimensional printing of CCTA and CMR models of the pulmonary valve and trunk for have been utilized for device design and procedural planning. [76][77][78][79] Percutaneous tricuspid valve procedures are at a very early stage of development and application,. [80][81][82][83][84][85] Preprocedural planning using CCTA and CMR cross sectional dynamic annular assessment and relationships to the right coronary artery are important to tricuspid valvular devices deployment.…”

Section: Virtual Planning For Valvular Heart Diseasementioning

confidence: 99%

Virtual medicine: Utilization of the advanced cardiac imaging patient avatar for procedural planning and facilitation

Shinbane

Saxon

2018

Journal of Cardiovascular Computed Tomography

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Advances in imaging technology have led to a paradigm shift from planning of cardiovascular procedures and surgeries requiring the actual patient in a "brick and mortar" hospital to utilization of the digitalized patient in the virtual hospital. Cardiovascular computed tomographic angiography (CCTA) and cardiovascular magnetic resonance (CMR) digitalized 3-D patient representation of individual patient anatomy and physiology serves as an avatar allowing for virtual delineation of the most optimal approaches to cardiovascular procedures and surgeries prior to actual hospitalization. Pre-hospitalization reconstruction and analysis of anatomy and pathophysiology previously only accessible during the actual procedure could potentially limit the intrinsic risks related to time in the operating room, cardiac procedural laboratory and overall hospital environment. Although applications are specific to areas of cardiovascular specialty focus, there are unifying themes related to the utilization of technologies. The virtual patient avatar computer can also be used for procedural planning, computational modeling of anatomy, simulation of predicted therapeutic result, printing of 3-D models, and augmentation of real time procedural performance. Examples of the above techniques are at various stages of development for application to the spectrum of cardiovascular disease processes, including percutaneous, surgical and hybrid minimally invasive interventions. A multidisciplinary approach within medicine and engineering is necessary for creation of robust algorithms for maximal utilization of the virtual patient avatar in the digital medical center. Utilization of the virtual advanced cardiac imaging patient avatar will play an important role in the virtual health care system. Although there has been a rapid proliferation of early data, advanced imaging applications require further assessment and validation of accuracy, reproducibility, standardization, safety, efficacy, quality, cost effectiveness, and overall value to medical care.

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Three-dimensional printing in vitro simulation of percutaneous pulmonary valve implantation in large right ventricular outflow tract

Cited by 11 publications

References 0 publications

Living the heart in three dimensions: applications of 3D printing in CHD

Living the heart in three dimensions: applications of 3D printing in CHD

Percutaneous Pulmonary Valve Implantation: Current Status and Future Perspectives

Virtual medicine: Utilization of the advanced cardiac imaging patient avatar for procedural planning and facilitation

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