Three-dimensional printed poly(l-lactide) copolymers with nano-hydroxyapatite scaffolds for enhanced osteogenic and regenerative activities in bone tissue engineering

Human umbilical cord blood mononuclear cells laden hydrogels made from carboxymethyl chitosan and oxidized hyaluronic acid for wound healing

“…It has been reported that 3D ECM gels can promote the growth of stem cells 24 . HA based hydrogels attracted much interest for applications in drug delivery, wound healing and tissue engineering due to their outstanding biocompatibility and biodegradability 25–27 . The oxidation of HA generates aldehyde‐containing HA (A‐HA) whose aldehyde groups can react with amino groups to form hydrogels by Schiff base reaction 28 .…”

“…24 HA based hydrogels attracted much interest for applications in drug delivery, wound healing and tissue engineering due to their outstanding biocompatibility and biodegradability. [25][26][27] The oxidation of HA generates aldehyde-containing HA (A-HA) whose aldehyde groups can react with amino groups to form hydrogels by Schiff base reaction. 28 The resulted dynamic hydrogels were used for postoperative adhesion prevention, abdominal tissue repair, or wound dressing.…”

Poly(trimethylene carbonate)‐b‐poly(ethylene glycol) diblock copolymer micelles for hydrophobic drug delivery: The effect of hydrophilic/hydrophobic segment length on micellar properties and drug loading

“…4,5 Among these systems, there has been considerable interest in the use of polymeric micelles delivery systems composed of biocompatible, biodegradable amphiphilic diblock copolymers. [6][7][8][9] These copolymers are composed of a hydrophobic block, such as poly(lactic acid), poly(lactic-coglycolic acid) and poly(caprolactone), and a hydrophilic block which is typically poly(ethylene glycol) (PEG). [10][11][12] These amphiphilic block copolymers are able to self-assemble in aqueous media to form micelles with a core-shell structure, which are composed of a hydrophobic core surrounded by a highly water bond hydrophilic PEG corona.…”

“…A search for improving the solubility of hydrophobic drugs has led to the application of many drug delivery systems such as parenteral emulsion, liposomes, nanoparticles, polymeric micelles, and conjugates 4,5 . Among these systems, there has been considerable interest in the use of polymeric micelles delivery systems composed of biocompatible, biodegradable amphiphilic diblock copolymers 6–9 . These copolymers are composed of a hydrophobic block, such as poly(lactic acid), poly(lactic‐co‐glycolic acid) and poly(caprolactone), and a hydrophilic block which is typically poly(ethylene glycol) (PEG) 10–12 .…”