Three-dimensional printed calcaneal prosthesis following total calcanectomy

Imanishi, Jungo; Choong, Peter F. M.

doi:10.1016/j.ijscr.2015.02.037

Cited by 120 publications

(95 citation statements)

References 16 publications

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“…The early case series are encouraging in various field of complex orthopaedic procedures, like bone tumour surgery [8][9][10]14], revision hip surgery [6,7,11], spinal implants [12][13][14] and trauma fracture fixation and reconstruction [15,16]. The additive manufacturing technology may address the reconstructive challenges that off-the-shelf, standard implants cannot provide for implant-size or disease-specific surgical requirement.…”

Section: Clinical Applications Of Am Orthopaedic Implantsmentioning

confidence: 99%

“…AM metallic implants have the great potential to customise the reconstructive needs at various locations of patients' skeleton. AM patient-specific implants have recently been applied for reconstruction in clavicular, scapular, calcaneal, pelvic and sacral bone tumours, which have complex bony geometry and no off-the-shelf implants available for bone reconstruction [8][9][10]14]. A case series of three patients with clavicle, scapular and pelvic bone sarcoma underwent tumour resection, and the bone defects were reconstructed with EBM fabricated titanium prostheses.…”

Section: Clinical Applications Of Am Orthopaedic Implantsmentioning

confidence: 99%

“…The standard traditional implants may not address the reconstructive challenges such as severe bone deformity or bone loss after implant loosening and bone tumour resection. With the advent of digital technologies in medical imaging, computer programming in three-dimensional (3D) modelling [1] and computer-assisted tools [2][3][4][5] in precise implant placement, there has been increasing interest in using patientspecific implants for complex orthopaedic reconstruction [6][7][8][9][10][11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

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Additive manufactured metallic implants for orthopaedic applications

Wong

Scheinemann

2018

Sci. China Mater.

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Metallic implants are commonly used in various orthopaedic surgeries, like fracture fixation, spinal instrumentation, joint replacement and bone tumour surgery. Patients may need to adapt to the fixed dimensions of the standard implants. It may result in suboptimal fit to the host bones and possible adverse clinical results. The standard traditional implants may not address the reconstructive challenges such as severe bone deformity or bone loss after implant loosening and bone tumour resection. With the advent of digital technologies in medical imaging, computer programming in three-dimensional (3D) modelling and computer-assisted tools in precise placement of implants, patient-specific implants (PSI) have gained more attention in complex orthopaedic reconstruction. Additive manufacturing technology, in contrast to the conventional subtractive manufacturing, is a flexible process that can fabricate anatomically conforming implants that match the patients' anatomy and surgical requirements. Complex internal structures with porous scaffold can also be built to enhance osseointegration for better implant longevity. Although basic studies have suggested that additive manufactured (AM) metal structures are good engineered biomaterials for bone replacement, not much peer-reviewed literature is available on the clinical results of the new types of implants. The article gives an overview of the metallic materials commonly used for fabricating orthopaedic implants, describes the metal-based additive manufacturing technology and the processing chain in metallic implants; discusses the features of AM implants; reports the current status in orthopaedic surgical applications and comments on the challenges of AM implants in orthopaedic practice.

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Section: Clinical Applications Of Am Orthopaedic Implantsmentioning

confidence: 99%

Section: Clinical Applications Of Am Orthopaedic Implantsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Additive manufactured metallic implants for orthopaedic applications

Wong

Scheinemann

2018

Sci. China Mater.

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“…Currently, the focus is mainly on the use of 3D to prepare the operative procedure, and to improve the surgical outcome (reduction) [12]. But some have taken steps even further and have implanted a 3D printed titanium calcaneus prosthesis following resection [13].…”

mentioning

confidence: 99%

3D Printing Calcaneal Fractures: Continuously Improving our Care by Making a Complex Problem Tangible

Schepers¹,

Misselyn

2017

Journal of Investigative Surgery

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“…This continued need for resorbable bone graft substitutes has given rise to the explosive new $850 million market for bone graft substitute materials, led by biomedical companies such as Medtronic, Stryker, DePuy Synthes, Wright Medical, Zimmer and many others (Dyrda, 2015 (Murphy & Atala, 2014); the materials, structural and biological properties of which will now be discussed. printed titanium replacements (Aranda, Jiménez, Rodríguez, & Varela, 2015;Imanishi & Choong, 2015).…”

Section: Tissue Engineering and Bone Regenerationmentioning

confidence: 99%

[leave for Adam - copyright supporting evidence]Designing patient-specific melt-electrospun scaffolds for bone regeneration

Paxton¹

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Biofabrication, or the 3D printing of biological-relevant tissues, is revolutionising our ability to treat patients who have suffered tissue loss as a result of trauma, disease or birth defect. As a subset of the Tissue Engineering field, biofabrication research is focussing on optimising the fabrication of implantable constructs, known as scaffolds, which provide a support structure for cell infiltration and growth, ultimately dissolving and restoring tissue, completely healing the patient.While research has focused on developing the mechanical capability to print structures using 3D printing, alongside biological advances to create highly biocompatible, bioactive constructs which have enhanced regenerative properties, less research has focused on developing methods of designing scaffolds which are anatomically matched to individual patients.In this thesis, a novel method for designing patient-specific scaffold for bone regeneration, to be fabricating using the melt-electrospinning 3D printing technique, was developed. The method was then applied to three clinically-relevant case studies, examining how to accurately design scaffolds to treat a wide range of orthopaedic injuries. Medical scan data was obtained from two patients and a third defect was recreated from an anatomical skull model. Following data acquisition, scaffolds were designed using 3D modelling software and processed into slices. These slices were processed by a proprietary g-code generation program which automatically generates the required computer instructions to fabricate each of the suitable layers using a meltelectrospinning machine. A skull scaffold to treat a large cranial defect, a femur scaffold to fill a void after a realignment procedure and a patella scaffold to improve the external shape of the reconstructed bone were successfully designed. The computer instructions were then trialled on the melt-electrospinning machine to assess the success of the generated g-code.In collaboration with the Biofabrication and Tissue Morphology group at the Queensland University of Technology, as well as the Orthopaedic Unit at the Royal Brisbane Hospital, this research project has successfully demonstrated the ability to fabricate patient-specific scaffolds, which one day could be used clinically to treat patients suffering from bone loss.

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Three-dimensional printed calcaneal prosthesis following total calcanectomy

Cited by 120 publications

References 16 publications

Additive manufactured metallic implants for orthopaedic applications

Additive manufactured metallic implants for orthopaedic applications

3D Printing Calcaneal Fractures: Continuously Improving our Care by Making a Complex Problem Tangible

[leave for Adam - copyright supporting evidence]Designing patient-specific melt-electrospun scaffolds for bone regeneration

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