Three-dimensional Physical Modeling: Applications and Experience at Mayo Clinic

Matsumoto, Jane S.; Morris, Jonathan M.; Foley, Thomas A.; Williamson, Eric E.; Leng, Shuai; McGee, Kiaran P.; Kuhlmann, Joel; Nesberg, Linda E.; Vrtiska, Terri J.

doi:10.1148/rg.2015140260

Cited by 145 publications

(107 citation statements)

References 71 publications

(66 reference statements)

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“…Three-dimensional (3D) printing (rapid prototyping, additive manufacturing) is a technology which manufactures a 3D object with a predesigned, computerized model commonly in a layerby-layer manner [1]. Medical 3D printing consists mainly of the following steps: image acquisition, virtual reconstruction and 3D manufacturing [2].…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional printing in cardiology: Current applications and future challenges

et al. 2017

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Section: Introductionmentioning

confidence: 99%

Three-dimensional printing in cardiology: Current applications and future challenges

et al. 2017

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“…Additive manufacturing, or three-dimensional (3-D) printing, has been widely used in industry and recently its application in medicine has been explored. [25][26][27][28][29][30][31] Compared to conventional phantom manufacturing, 3-D printing techniques have the advantage of constructing complex physical objects in a shorter time and with less effort. This flexibility enables fast construction of patient-specific models for individualized medicine.…”

Section: Introductionmentioning

confidence: 99%

Construction of realistic phantoms from patient images and a commercial three-dimensional printer

et al. 2016

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Abstract. The purpose of this study was to use three-dimensional (3-D) printing techniques to construct liver and brain phantoms having realistic pathologies, anatomic structures, and heterogeneous backgrounds. Patient liver and head computed tomography (CT) images were segmented into tissue, vessels, liver lesion, white and gray matter, and cerebrospinal fluid (CSF). Stereolithography files of each object were created and imported into a commercial 3-D printer. Printing materials were assigned to each object after test scans, which showed that the printing materials had CT numbers ranging from 70 to 121 HU at 120 kV. Printed phantoms were scanned on a CT scanner and images were evaluated. CT images of the liver phantom had measured CT numbers of 77.8 and 96.6 HU for the lesion and background, and 137.5 to 428.4 HU for the vessels channels, which were filled with iodine solutions. The difference in CT numbers between lesions and background (18.8 HU) was representative of the low-contrast values needed for optimization tasks. The liver phantom background was evaluated with Haralick features and showed similar texture between patient and phantom images. CT images of the brain phantom had CT numbers of 125, 134, and 108 HU for white matter, gray matter, and CSF, respectively. The CT number differences were similar to those in patient images.

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“…While thinner slices offer more accurate delineation of anatomy, the lower signal-to-noise ratio may limit or even prohibit segmentation of the tissues, particularly in the presence of streak or susceptibility artifact from metal when using CT or MRI data, respectively. For CT isotropic volumetric data should be reconstructed using slice thicknesses of 1–3 mm for thoracic 3D printing [28] and 0.5–1.25 mm for cardiac 3D printing [19, 29]. For CT, the selection of appropriate image reconstruction technique including reconstruction kernel and adaptive image reconstruction technologies can be used advantageously.…”

Section: Imaging Considerationsmentioning

confidence: 99%

Cardiothoracic Applications of 3-dimensional Printing

Giannopoulos

Steigner

George

et al. 2016

Journal of Thoracic Imaging

142

108

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Summary Medical 3D printing is emerging as a clinically relevant imaging tool in directing preoperative and intraoperative planning in many surgical specialties and will therefore likely lead to interdisciplinary collaboration between engineers, radiologists, and surgeons. Data from standard imaging modalities such as CT, MRI, echocardiography and rotational angiography can be used to fabricate life-sized models of human anatomy and pathology, as well as patient-specific implants and surgical guides. Cardiovascular 3D printed models can improve diagnosis and allow for advanced pre-operative planning. The majority of applications reported involve congenital heart diseases, valvular and great vessels pathologies. Printed models are suitable for planning both surgical and minimally invasive procedures. Added value has been reported toward improving outcomes, minimizing peri-operative risk, and developing new procedures such as transcatheter mitral valve replacements. Similarly, thoracic surgeons are using 3D printing to assess invasion of vital structures by tumors and to assist in diagnosis and treatment of upper and lower airway diseases. Anatomic models enable surgeons to assimilate information more quickly than image review, choose the optimal surgical approach, and achieve surgery in a shorter time. Patient-specific 3D-printed implants are beginning to appear and may have significant impact on cosmetic and life-saving procedures in the future. In summary, cardiothoracic 3D printing is rapidly evolving and may be a potential game-changer for surgeons. The imager who is equipped with the tools to apply this new imaging science to cardiothoracic care is thus ideally positioned to innovate in this new emerging imaging modality.

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Three-dimensional Physical Modeling: Applications and Experience at Mayo Clinic

Cited by 145 publications

References 71 publications

Three-dimensional printing in cardiology: Current applications and future challenges

Three-dimensional printing in cardiology: Current applications and future challenges

Construction of realistic phantoms from patient images and a commercial three-dimensional printer

Cardiothoracic Applications of 3-dimensional Printing

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