Three-dimensional optical coherence tomographic findings in central serous chorioretinopathy

Mitarai, Kosuke; Gomi, Fumi; Tano, Yasuo

doi:10.1007/s00417-006-0277-7

Cited by 88 publications

(51 citation statements)

References 15 publications

(20 reference statements)

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“…However, PED prevalence may vary from 8% to 71% [11,18,19,22]. In our study, OCT did not show any PED in female cases.…”

Section: Discussioncontrasting

confidence: 60%

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Comparison of optical coherence tomography findings in males and females with acute central serous chorioretinopathy

Karanfil¹

2017

New Front Ophthalmol

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Objective: To compare the optical coherence tomography (OCT) findings in males and females with acute central serous chorioretinopathy (CSCR). Materials and methods:In this retrospective study, the OCT scans of 8 females (Group 1) and 16 males (Group 2) cases with acute CSCR which were diagnosed based on clinical, ophthalmological and OCT findings and which was followed in our hospital were retrospectively reviewed. The existence of the OCT findings and patterns regarding CSCR and sub-foveal choroidal thicknesses (SFCTs) were compared.Results: Serous macula detachment (SMD) was present in all of the female and male cases. The most common OCT finding was the brush-border pattern (6 cases, 75%) except SMD and retina pigment epithelium (RPE) bulging in females, and RPE bulging (14 cases, 87.5%) except SMD in males. There was no statistically significant difference in the frequency of OCT findings and patterns between both groups (p>0.05). The mean SFCTs of the eyes with CSCR in Group 1 and Group 2 were 346.08±32.1 µm (ranged from 338 to 365 µm) and 351.32±36.5 µm (ranged from 344 to 376 µm), respectively. The difference between SFCTs in the affected eyes was also not statistically significant (p>0.05).

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“…However, PED prevalence may vary from 8% to 71% [11,18,19,22]. In our study, OCT did not show any PED in female cases.…”

Section: Discussioncontrasting

confidence: 60%

“…The most common spectral domain OCT findings detected in the patients with acute CSCR are PED, RPE bulging, SMD, dipping pattern, brush-border pattern or elongation of photoreceptor outer segments and IHRDs or SHRDs [2,13,[17][18][19][20][21].…”

Section: Discussionmentioning

confidence: 99%

Comparison of optical coherence tomography findings in males and females with acute central serous chorioretinopathy

Karanfil¹

2017

New Front Ophthalmol

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“…FFA shows a focal RPE leak with pooling of the dye in the overlying serous retinal detachment. 4 The morphological alterations occurring at the site of focal leak have been studied and reported to show RPE abnormalities including an RPE bulge in the posterior pole, 9 RPE detachments, 9-13 reproducible small RPE bulge (which researchers did not consider to be PEDs or artifactual), 11 irregular lesions of RPE, 14 and more recently, RPE disruption indicating an anatomical microrip of RPE. shows PED as a complete ring (thick arrow) and retinal pigment epithelium breech corresponding to the point of leak (thin arrow) (top left).…”

Section: Discussionmentioning

confidence: 99%

Spontaneous closure of retinal pigment epithelium microrip in the natural course of central serous chorioretinopathy

Gupta

Dogra

et al. 2009

Eye

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Purpose To study the natural course of changes observed in the retinal pigment epithelium (RPE) on spectral domain OCT transverse and RPE fit C-scans corresponding to the leakage point observed on fundus fluorescein angiograms in central serous chorioretinopathy (CSC). Methods Thirteen patients with acute CSC were prospectively enrolled and followed up for 6 months. All were examined using Zeiss Cirrus HD-OCT Model 4000. Transverse and RPE fit C-scans corresponding to point of leakage were superimposed on an OCT fundus photograph and correlated with the leakage point on a fluorescein angiogram. The RPE alterations observed at the leakage point were noted at presentation and follow-up. Results Transverse and RPE fit C-scans showed an irregularity of RPE resembling a 'honeycomb' pattern in 11 (85%) eyes at the point corresponding to the fluorescein leakage site. These were observed as pigment epithelium detachment (PED) on Raster line scan. Six of these 11 eyes (54.5%) showed a disruption/breach in the RPE on transverse C-scan and on RPE fit C-scan. All eyes showed a resolution of subretinal fluid with a closure of microrip, and the honeycombed pattern at the leakage site was replaced with RPE hypertrophy. Conclusion RPE microrips show spontaneous closure in the natural course of CSC.

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“…However, this treatment is controversial, because comparable visual outcomes are normally achieved over time with no intervention and no risks of adverse effects [31,32]. Recent studies in eyes with chronic CSC have demonstrated a spatial correlation between the ALS at fluorescein angiography and RPE alterations on optical coherence tomography (OCT) [33][34][35]. This observation suggests that persistent leak and sub-retinal fluid can lead to permanent RPE changes, which cause irreversible visual loss [36].…”

Section: Discussionmentioning

confidence: 96%

Indocyanine green enhanced subthreshold diode-laser micropulse photocoagulation treatment of chronic central serous chorioretinopathy

Ricci

Missiroli

Regine

et al. 2008

Graefes Arch Clin Exp Ophthalmol

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Three-dimensional optical coherence tomographic findings in central serous chorioretinopathy

Abstract: OCT-ophthalmoscope detects morphologic changes easily and noninvasively at the point of dye leakage in eyes with CSC.

Cited by 88 publications

References 15 publications

Comparison of optical coherence tomography findings in males and females with acute central serous chorioretinopathy

Comparison of optical coherence tomography findings in males and females with acute central serous chorioretinopathy

Spontaneous closure of retinal pigment epithelium microrip in the natural course of central serous chorioretinopathy

Indocyanine green enhanced subthreshold diode-laser micropulse photocoagulation treatment of chronic central serous chorioretinopathy

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