This research article deals with the nonlinear thermally radiated influences on non-Newtonian nanofluid considering Jeffrey fluid in a rotating system. The governing equations of the nanofluid have been transformed to a set of differential nonlinear equations, using suitable similarity variables. The Homotopy Analysis Method (HAM) and Runge–Kutta Method of order 4 (RK Method of order 4) are used for the solution of the modeled problem. The variation of the skin friction, Nusselt number, Sherwood number, and their impacts on the velocity distribution, temperature distribution, and concentration distribution have been examined. The influence of the Hall effect, rotation, Brownian motion, porosity, and thermophoresis analysis are also investigated. Moreover, for comprehension of the physical presentation of the embedded parameters, Deborah number
β
, viscosity parameter
R
, rotation parameter
Kr
, Brownian motion parameter
Nb
, porosity parameter
γ
, magnetic parameter
M
, Prandtl number
Pr
, thermophoretic parameter
Nt
, and Schmidt number
Sc
have been plotted and deliberated graphically. For large values of Brownian parameter, the kinetic energy increases, which in turn increases the temperature distribution, while the thermal boundary layer thickness decreases by increasing the radiation parameter, and the Hall parameter increases the motion of the fluid in horizontal direction. Also, the mass flux has been observed as a decreasing function at the lower stretching plate.