Three-dimensional Imaging of Macular Holes with High-speed Optical Coherence Tomography

Hangai, Masanori; Ojima, Yumiko; Gotoh, Noriko; Inoue, Ryo; Yasuno, Yoshiaki; Makita, Shuichi; Yamanari, Masahiro; Yatagai, Toyohiko; Kita, Mihori; Yoshimura, Nagahisa

doi:10.1016/j.ophtha.2006.07.055

Cited by 167 publications

(95 citation statements)

References 30 publications

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“…The method, which is based on low coherence interferometry, was first presented by Huang et al [18]. In medicine, OCT is currently primarily used in ophthalmology for evaluating the pathological changes in retinal layers and the optic nerve [19][20][21][22]. Further applications are found in dermatology [23,24] and cardiology [25].…”

Section: Introductionmentioning

confidence: 99%

Dental Applications of Optical Coherence Tomography (OCT) in Cariology

et al. 2017

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Across all medical disciplines, therapeutic interventions are based on previously acquired diagnostic information. In cariology, which includes the detection and assessment of the disease "caries" and its lesions, as well as non-invasive to invasive treatment and caries prevention, visual inspection and radiology are routinely used as diagnostic tools. However, the specificity and sensitivity of these standard methods are still unsatisfactory and the detection of defects is often afflicted with a time delay. Numerous novel methods have been developed to improve the unsatisfactory diagnostic possibilities in this specialized medical field. These newer techniques have not yet found widespread acceptance in clinical practice, which might be explained by the generated numerical or color-coded output data that are not self-explanatory. With optical coherence tomography (OCT), an innovative image-based technique has become available that has considerable potential in supporting the routine assessment of teeth in the future. The received cross-sectional images are easy to interpret and can be processed. In recent years, numerous applications of OCT have been evaluated in cariology beginning with the diagnosis of different defects up to restoration assessment and their monitoring, or the visualization of individual treatment steps. Based on selected examples, this overview outlines the possibilities and limitations of this technique in cariology and restorative dentistry, which pertain to the most clinical relevant fields of dentistry.

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Section: Introductionmentioning

confidence: 99%

Dental Applications of Optical Coherence Tomography (OCT) in Cariology

et al. 2017

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“…It also provides consecutive orthogonal images that allow much more precise and minute observation of threedimensionally extending intraretinal structural changes associated with a macular hole than conventional OCT imaging, including the involvement of the photoreceptor cells in macular holes. 30 These recent advances in OCT imaging promise to improve the understanding of disease progression and its management.…”

Section: Pathogenesis Of Macular Holesmentioning

confidence: 99%

Macular holes: vitreoretinal relationships and surgical approaches

Bainbridge

Herbert

Gregor

2008

Eye

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Idiopathic full-thickness macular holes develop as a result of anteroposterior and tangential traction exerted by the posterior vitreous cortex at the fovea. Vitreoretinal relationships during the development of macular holes can be demonstrated in detail by ocular coherence tomography, facilitating an improved understanding of their pathogenesis and guiding clinical management. Surgical strategies for the repair of macular holes are designed to relieve vitreofoveal traction and to promote flattening and reapposition of the macular hole edges by intraocular gas tamponade. A period of facedown positioning postoperatively is conventionally advised. However, the evidence to support this recommendation is weak and practice varies considerably. Surgical removal of the inner limiting membrane (ILM) is advocated to ensure thorough removal of any tangential tractional components including any residual cortical vitreous. Current evidence suggests that ILM peeling can improve anatomical outcomes but the effect on visual function is less predictable; unsuccessful attempts to peel the ILM can be associated with poor visual outcome. The use of vital dyes can facilitate visualisation of the ILM and help achieve complete, atraumatic peeling. Indocyanine green dye can enable high rates of macular hole closure but has been associated with poorer visual outcomes suggesting a dosedependent toxicity. Trypan blue dye offers an alternative that may have a more favourable risk profile. An improved understanding of vitreoretinal relationships may facilitate a tailored approach to surgery in individuals with macular holes. Vitrectomy to relieve anteroposterior traction is central in the management of all full-thickness holes. The use of long-acting gases, prolonged face-down positioning, and ILM peeling may be more valuable for larger holes, longstanding holes, and those that have failed to close following conventional surgery.

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“…After collecting A-scan, combining a series of these axial depth scans to form a crosssectional tomography is called a "B-scan". Up to now, OCT has been already widely used in clinical application such as ophthalmology [2][3][4][5][6] and dentistry [7][8][9][10]. OCT is currently divided into two main categories: time-domain OCT (TD-OCT) and frequency-domain OCT (FD-OCT).…”

Section: Introductionmentioning

confidence: 99%

Systematic Optimization for Optical Coherence Tomographic Imaging

Chen¹,

Sun²

2017

Optical Data Processing and Storage

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Abstract:Optical coherence tomography is a powerful tool that can e ectively provide detail information of biological tissue structure. The axis resolution of optical coherence tomography has achieved sub-micrometer and we are interested in its ultrahigh resolution that can be practically utilized for clinical application. In this article, the basic system calibration is discussed; we systematically demonstrated the detail process in optimization of optical coherence tomography for accurately acquiring data. The systematic optimization for optical coherence tomography imaging is discussed here including system calibration and image post-processing.

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Three-dimensional Imaging of Macular Holes with High-speed Optical Coherence Tomography

Cited by 167 publications

References 30 publications

Dental Applications of Optical Coherence Tomography (OCT) in Cariology

Dental Applications of Optical Coherence Tomography (OCT) in Cariology

Macular holes: vitreoretinal relationships and surgical approaches

Systematic Optimization for Optical Coherence Tomographic Imaging

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