Background: Catheter of atrial fibrillation is still challenging because of the high degree of variability of the pulmonary vein anatomy. Therefore, 3D imaging systems are frequently used prior to an ablation procedure. Three-dimensional transesophageal echocardiography provides an excellent overview over the individual left atrial morphology without some of the limitations associated with other imaging techniques. Methods: In 50 patients, three-dimensional transesophageal echocardiography was performed immediately prior to an ablation procedure. The images were available throughout the ablation procedure. In most of the patients with paroxysmal atrial fibrillation, the cryoablation technique was used (Arctic Front Balloon, CryoCath Technologies/Medtronic; group A2). In the other patients, a