Three-dimensional drug printing: A structured review

Ursan, Iulia D.; Chiu, Ligia; Pierce, Andrea

doi:10.1331/japha.2013.12217

Cited by 193 publications

(108 citation statements)

References 23 publications

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“…Additive manufacturing (commonly referred to as 3D printing) of pharmaceuticals with inkjet printing is focused entirely on powder-bed technologies (Wu et al 1996, Ursan et al 2013, Khaled et al 2014. A combination of a powder and a binder 'ink' is used to construct solid macroscopic structures in a layer-by-layer process.…”

Section: D Printing (3dp)mentioning

confidence: 99%

Inkjet printing for pharmaceutics – A review of research and manufacturing

Daly

Harrington

Martin

et al. 2015

International Journal of Pharmaceutics

263

185

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Abstract:Global regulatory, manufacturing and consumer trends are driving a need for change in current pharmaceutical sector business models, with a specific focus on the inherently expensive research costs, high-risk capital-intensive scale-up and the traditional centralised batch manufacturing paradigm. New technologies, such as inkjet printing, are being explored to radically transform pharmaceutical production processing and the end-to-end supply chain. This review provides a brief summary of inkjet printing technologies and their current applications in manufacturing before examining the business context driving the exploration of inkjet printing in the pharmaceutical sector. We then examine the trends reported in the literature for pharmaceutical printing, followed by the scientific considerations and challenges facing the adoption of this technology. We demonstrate that research activities are highly diverse, targeting a broad range of pharmaceutical types and printing systems. To mitigate this complexity we show that by categorising findings in terms of targeted business models and Active Pharmaceutical Ingredient (API) chemistry we have a more coherent approach to comparing research findings and can drive efficient translation of a chosen drug to inkjet manufacturing.

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Section: D Printing (3dp)mentioning

confidence: 99%

Inkjet printing for pharmaceutics – A review of research and manufacturing

Daly

Harrington

Martin

et al. 2015

International Journal of Pharmaceutics

263

185

View full text Add to dashboard Cite

show abstract

“…For example, the use of 3D printing to customize prosthetics and implants can provide great value for both patients and physicians and can associated with more precise results and less complications. In addition, Custom-made implants, fixtures, and surgical tools can have a positive impact in terms of the time required for surgery, patient recovery time, and the success of the surgery or implant [18].…”

Section: D Printing and Customized Implantsmentioning

confidence: 99%

“…This is also true in neurosurgery: Skulls have irregular shapes, so it is hard to standardize a cranial implant. 3 In victims of head injury, where bone is removed to give the brain room to swell, the cranial plate that is later fitted must be perfect.9 Although some plates are milled, more and more are created using 3D printers, which makes it much easier to customize the fit and design [16][17][18][19][20][21].…”

Section: D Printing and Customized Implantsmentioning

confidence: 99%

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The Cutting Edge in Oral and Maxillofacial Surgery

Hegab¹

2015

J Oral Hyg Health

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The vision for the future with advanced technology and science for easy and better treatments outcome motivating the clinicians to look-forward to practical the cutting edge tactics in the Oral and Maxillofacial Surgery. The results will be providing the patients with first-class medical services with reduction of the treatment morbidity. Greater progress has been made in the field of the Oral and Maxillofacial Surgery. In the last decades, the researchers were concentered on the improvement of the preoperative planning as it plays a vital role in the success rate of the surgical procedures. Now, as a result of the advanced computer technology, the researches extend beyond the scope of planning and moving toward the surgical procedures itself.Evolution over the last decades focused toward improvement of the preoperative planning, minimally invasive approaches, and minimizing the operation time. All aiming to decrease surgical complications and less post-operative pain and rapid return to normal life-style activities. As a result; remarkable recent advances in surgical and computer technology are evolving every day. Innovations in Oral and Maxillofacial Surgery have allowed the professions to progress at a very fast rate and looked-for for more every day. The increased accuracy and speed of treatment, along with reduced discomfort, and decreased the complications will be the actual advantages to our patients.The aim of the current review is to give an insight about the cutting edge in the field of oral and maxillofacial surgery to provide a more detailed physical manifestation of your mental picture and a new dimension of insight into the clinical situations you encounter every day.

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“…This technology has been applied in numerous fields, representing the large variety of possible applications, including the consumer goods industry [1] , aerospace research [2,3] , regenerative medicine [4][5][6][7][8][9][10][11][12] , medical device development [13][14][15][16][17][18][19] and the automotive industry [20] . An emerging application of 3D printing is for drug manufacturing [21,22] . Interest in 3D printing of pharmaceutical products has been growing since the Food and Drug Administration (FDA) approved the first 3D printed drug in 2015 [1,21] .…”

Section: Introductionmentioning

confidence: 99%

3D printing for drug manufacturing: A perspective on the future of pharmaceuticals

Lepowsky¹

2024

IJB

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Since a three-dimensional (3D) printed drug was first approved by the Food and Drug Administration in 2015, there has been a growing interest in 3D printing for drug manufacturing. There are multiple 3D printing methods -including selective laser sintering, binder deposition, stereolithography, inkjet printing, extrusion-based printing, and fused deposition modeling -which are compatible with printing drug products, in addition to both polymer filaments and hydrogels as materials for drug carriers. We see the adaptability of 3D printing as a revolutionary force in the pharmaceutical industry. Release characteristics of drugs may be controlled by complex 3D printed geometries and architectures. Precise and unique doses can be engineered and fabricated via 3D printing according to individual prescriptions. On-demand printing of drug products can be implemented for drugs with limited shelf life or for patient-specific medications, offering an alternative to traditional compounding pharmacies. For these reasons, 3D printing for drug manufacturing is the future of pharmaceuticals, making personalized medicine possible while also transforming pharmacies.

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Three-dimensional drug printing: A structured review

Cited by 193 publications

References 23 publications

Inkjet printing for pharmaceutics – A review of research and manufacturing

Inkjet printing for pharmaceutics – A review of research and manufacturing

The Cutting Edge in Oral and Maxillofacial Surgery

3D printing for drug manufacturing: A perspective on the future of pharmaceuticals

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