Three‐dimensional coordination polymers based on trimethyltin cation with nicotinic and isonicotinic acids as anticancer agents

Abstract

Two new coordination polymers, namely [Me3Sn(INA)] (CP1) and [Me3Sn(NA)] (CP2), where INA = isonicotinic acid and NA = nicotinic acid, were characterized using infrared, UV–visible and NMR spectroscopies, thermogravimetric analysis and single‐crystal X‐ray analyses. The structure of CP1 consists of a one‐dimensional coordinated chain which is further extended creating a two‐dimensional layer via hydrogen bonds. The two‐dimensional layers propagate along the corresponding planes creating a three‐dimensional framework by hydrogen bonding and edge‐to‐face π–π stacking. The asymmetric unit of CP2 contains one tin atom and one NA ligand exhibiting 1:1 stoichiometry. The structure of CP2 extends through coordination bonds to form a one‐dimensional zigzag chain which further extends to create a three‐dimensional network via crossing chains and hydrogen bonds. The tin atoms acquire distorted trigonal bipyramid (TBPY‐5) geometry. CP1 and CP2 were designed to investigate their cytotoxic properties against various human cancer cell lines: hepatocellular carcinoma, mammary gland breast cancer, human prostate cancer and colorectal carcinoma. The compounds are good anticancer agents against the tested cell lines. Also they were screened for their antioxidant, anti‐haemolytic, antibacterial and antifungal activities.

Crystal structure, characterization and catalytic activities of Cu(II) coordination complexes with 8‐hydroxyquinoline and pyrazine‐2‐carboxylic acid

“…Reactions of bivalent transition metal ions with ligands containing heterocyclic carboxylic acids derived from pyridines, quinoline, pyrazine and their homologous ring system have been extensively studied with respect to their bonding, electrochemical, spectroscopic properties, thermal, and magnetic behavior in addition to catalytic and photocatalytic activities . The development of new metal coordination complex catalysts for the oxidative decolorization of waste dyes continues to be a challenging topic in areas of heterogeneous catalysis and green chemistry …”

Structural studies and biological evaluation of Co (II), Ni (II) and Cu (II) complexes of carbohydrazone derived from ethyl acetoacetate in addition to crystallographic description of La (III) or Sm (III) catalytic activity abnormal product

“…The photoluminescence spectra of [Cu 2 (H 4 EBC)Cl 2 ]·H 2 O , [Co(H 4 EBC)Cl 2 (H 2 O) 2 ]·2H 2 O and [Ni(H 4 EBC)Cl 2 (H 2 O)]·2H 2 O display emission broad‐bands at 342, 321 and 337 nm, respectively (Figure ). These bands can be attributed to as ligand‐to‐metal charge transfer . On the other hand, H 4 EBC does not show any bands in DMSO solution on excitation.…”

Low temperature redetermination of the crystal structure of catena-poly[[tri-4-fluorobenzyltin(IV)]μ2-pyridine-4-carboxylato-κ2 N:O], {C27H22F3NO2Sn}n

“…The common feature of these structures is the presence of five-coordinate tin-atom geometries defined by trans-C 3 NO donor sets owing to the presence of µ 2 -pyridine-4carboxylato bridges. Thus, derivatives with R = methyl [12,13], n-butyl [14], cyclohexyl [15], benzyl [16], 2-chlorobenzyl [17], 2-fluorobenzyl [18], 4-fluorobenzyl [19], phenyl [20] and the mixed species R 3 = phenyl 2 (ethyl) [21] are known. The title compound, i.e.…”