Objectives
The hypothesis of this study was that there are multiple factors that are dominant in causing external apical root resorption (EARR). The objective of this investigation was to better understand the clinical factors that may lead to EARR.
Material and Methods
Maxillary cone-beam computed tomography (CBCT) scans of 18 subjects who were treated with bilateral canine retractions during orthodontics were used to calculate EARR. The subjects were treated using well-calibrated segmental T-loops for delivering a 124 cN retraction force and the moment-to-force ratio suitable for moving the canine under either translation or controlled tipping. The subjects’ age, gender, treatment duration, and genotypes were collected.
Results
Six subjects out of eighteen showed definite EARR, meaning that load was not the only causing factor. All five subjects with the genotype identified had G/G genotype of IL-1β rs11143634, indicating people with this genotype may be at high risk. Longer treatment duration, female, and older age may also contribute to EARR although the findings were not statistically significant.
Conclusion
EARR appears to be related to multiple factors. The orthodontic load and the genotype should be the focuses for future studies.