Three-dimensional acoustic monitoring of laser-accelerated protons in the focus of a pulsed-power solenoid lens

Gerlach, Sonja; Balling, F.; Schmidt, A.K.; Brack, F.E.; Kroll, F.; Metzkes-Ng, J.; Reimold, Marvin; Schramm, U.; Speicher, M.; Zeil, K.; Parodi, K.; Schreiber, J.

doi:10.1017/hpl.2023.16

Cited by 3 publications

(1 citation statement)

References 27 publications

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“…To capture the full solid angle, the spectral measurement is performed by absorbing the proton bunch in a detector volume, yielding the corresponding spatially resolved 3D dose distribution from which the energy spectrum is deconvoluted. Dose-based spectral characterization has been implemented with several detector types from stacks of radiochromic film (RCF) [10,15] to scintillators [16][17][18][19][20][21][22][23][24] and ultrasound-based methods [25,26] , yielding the angularly resolved spectrum with different granularity in either angle and/or energy. However, only scintillator-and ultrasoundbased approaches in principle allow for real-time readouts.…”

Section: Introductionmentioning

confidence: 99%

OCTOPOD: single-bunch tomography for angular-spectral characterization of laser-driven protons

Reimold

Assenbaum

Beyreuther

et al. 2023

High Pow Laser Sci Eng

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Laser–plasma accelerated (LPA) proton bunches are now applied for research fields ranging from ultra-high-dose-rate radiobiology to material science. Yet, the capabilities to characterize the spectrally and angularly broad LPA bunches lag behind the rapidly evolving applications. The OCTOPOD translates the angularly resolved spectral characterization of LPA proton bunches into the spatially resolved detection of the volumetric dose distribution deposited in a liquid scintillator. Up to 24 multi-pinhole arrays record projections of the scintillation light distribution and allow for tomographic reconstruction of the volumetric dose deposition pattern, from which proton spectra may be retrieved. Applying the OCTOPOD at a cyclotron, we show the reliable retrieval of various spatial dose deposition patterns and detector sensitivity over a broad dose range. Moreover, the OCTOPOD was installed at an LPA proton source, providing real-time data on proton acceleration performance and attesting the system optimal performance in the harsh laser–plasma environment.

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Section: Introductionmentioning

confidence: 99%

OCTOPOD: single-bunch tomography for angular-spectral characterization of laser-driven protons

Reimold

Assenbaum

Beyreuther

et al. 2023

High Pow Laser Sci Eng

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Toward real‐time, volumetric dosimetry for FLASH‐capable clinical synchrocyclotrons using protoacoustic imaging

Wang,

Gonzalez,

Owen

et al. 2024

Medical Physics

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BackgroundFast low angle shot hyperfractionation (FLASH) radiotherapy (RT) holds promise for improving treatment outcomes and reducing side effects but poses challenges in radiation delivery accuracy due to its ultra‐high dose rates. This necessitates the development of novel imaging and verification technologies tailored to these conditions.PurposeOur study explores the effectiveness of proton‐induced acoustic imaging (PAI) in tracking the Bragg peak in three dimensions and in real time during FLASH proton irradiations, offering a method for volumetric beam imaging at both conventional and FLASH dose rates.MethodsWe developed a three‐dimensional (3D) PAI technique using a 256‐element ultrasound detector array for FLASH dose rate proton beams. In the study, we tested protoacoustic signal with a beamline of a FLASH‐capable synchrocyclotron, setting the distal 90% of the Bragg peak around 35 mm away from the ultrasound array. This configuration allowed us to assess various total proton radiation doses, maintaining a consistent beam output of 21 pC/pulse. We also explored a spectrum of dose rates, from 15 Gy/s up to a FLASH rate of 48 Gy/s, by administering a set number of pulses. Furthermore, we implemented a three‐dot scanning beam approach to observe the distinct movements of individual Bragg peaks using PAI. All these procedures utilized a proton beam energy of 180 MeV to achieve the maximum possible dose rate.ResultsOur findings indicate a strong linear relationship between protoacoustic signal amplitudes and delivered doses (R2 = 0.9997), with a consistent fit across different dose rates. The technique successfully provided 3D renderings of Bragg peaks at FLASH rates, validated through absolute Gamma index values.ConclusionsThe protoacoustic system demonstrates effectiveness in 3D visualization and tracking of the Bragg peak during FLASH proton therapy, representing a notable advancement in proton therapy quality assurance. This method promises enhancements in protoacoustic image guidance and real‐time dosimetry, paving the way for more accurate and effective treatments in ultra‐high dose rate therapy environments.

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Ionoacoustic monitoring of relativistic heavy ion beams

Kirsch,

Assmann,

Gerlach

et al. 2023

Nuclear Instruments and Methods in Physics Research Section A:

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Three-dimensional acoustic monitoring of laser-accelerated protons in the focus of a pulsed-power solenoid lens

Cited by 3 publications

References 27 publications

OCTOPOD: single-bunch tomography for angular-spectral characterization of laser-driven protons

OCTOPOD: single-bunch tomography for angular-spectral characterization of laser-driven protons

Toward real‐time, volumetric dosimetry for FLASH‐capable clinical synchrocyclotrons using protoacoustic imaging

Ionoacoustic monitoring of relativistic heavy ion beams

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