Three cases of ruptured intracranial aneurysm in a family

A ten month old unconscious boy with hemiplegia (Hunt and Hess IV) was first admitted to a district hospital without a CT scanner or a neurosurgical service (Glasgow-Coma-Score 4, no pathological pupillary signs). Therefore, he was transferred to the Pediatric Department of the University Hospital the same night. An emergency CT scan that night showed intracerebral and subarachnoid hemorrhage with enlarged ventricle (Fisher grade 5). Angiography was not available within reasonable time. Thus in the stage of progressively increasing clinical deterioration, still without pupillary signs, an external ventricular drain-age was placed. Immediately after reduction of the cerebrospinal fluid volume, arterial hypertension was noticed--the right pupil was mydriatic and fixed. Without further apparative diagnosis an emergency craniotomy was performed for decompression under the suspicion of a secondary hemorrhage due to a rerupture of a middle cerebral artery aneurysm. A bleeding aneurysm of the right middle cerebral artery was found and clipped. A mass transfusion was necessary and a pulmonary air embolism occurred. The infant died in tabula. The histological specimens revealed disruption of the internal elastic membrane of both MCA. This emphasizes a congenital nature of the aneurysm. We conclude that cerebral arterial aneurysms have to be considered in the differential diagnosis of stroke-like symptoms in infancy and early childhood, although the incidence of reported cases is less than one case per year. Since no valid screening parameter is available, diagnosis is often made only after rupture of the aneurysm. This causes problems for emergency management. Infants and children with stroke or stroke-like symptoms should immediately be transferred to a hospital with a neurosurgical unit.

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Management of a ruptured cerebral aneurysm in infancy.—Report of a case of a ten-month-old boy

Hülsmann

Moskopp

Wassmann

1998

Neurosurg. Rev.

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Three cases of ruptured intracranial aneurysm in a family

Abstract: A family is reported in which three members had an aneurysm at the junction of the posterior cerebral artery and the carotid artery. Two patients harbonred symmetrically placed bilateral aneurysm each. The cases suggest a hereditary basis for its causation.

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Management of a ruptured cerebral aneurysm in infancy.—Report of a case of a ten-month-old boy

Management of a ruptured cerebral aneurysm in infancy.—Report of a case of a ten-month-old boy

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