Three- and four-coordinate Ag(I) complexes of crotonate and bis(benzimidazole)-2-oxapropane ligands: syntheses, crystal structures, DNA-binding studies and antioxidant activities

Abstract

Two V-shaped ligands, namely 1,3-bis(1-ethylbenzimidazol-2-yl)-2-oxapropane (etobb) and 1,3-bis(1-benzylbenzimidazol-2-yl)-2-oxapropane (bobb), have been prepared. Reaction of these ligands with AgNO 3 and sodium crotonate under in the dark afforded the complexes,Both complexes have been characterized by physicochemical and spectroscopic methods and also by X-ray single-crystal diffraction. The coordination environment of complex 1 can be described as distorted tetrahedral, while complex 2 has as a trigonal planar geometry. The DNA-binding properties of these complexes have been investigated by fluorescence, electronic absorption and viscosity measurements. The experimental results suggest that they bind to DNA by an intercalation mode. Complex 2 also exhibits excellent hydroxyl radical scavenging activity.

Coordinative Compounds Based on Unsaturated Carboxylate with Versatile Biological Applications

“…By using sodium crotonate, species [Ag(crot)(bobb)] 85 [99], [Ag(crot)(bebt)] 86 (bebt = 1,3-bis(1-ethylbenzimidazol-2-yl)-2-thiapropane) [100] and [Ag 2 (crot) 2 (aobb)] n 87 [101] were designed for the same purpose. The structural characterization of 85 revealed a mononuclear three-coordinate configuration, in which carboxylate acts as a unidentate and benzimidazole derivative as a chelate (Figure 5f) [99].…”

Energetic Features of H-Bonded and π-Stacked Assemblies in Pyrazole-Based Coordination Compounds of Mn(II) and Cu(II): Experimental and Theoretical Studies

“…Similarly, metal crotonate complexes also display different biological activities like DNA binding, radical scavenging activities, etc. [33]. In a similar way, pyrazole ligand complexes, with their diverse structural configurations, exhibit significant efficacy and versatility across various fields, including medicine, catalysis, separations, bio-mimetic chemistry, optics, magnetism, and luminescence [34][35][36][37].…”

Synthesis, crystal structure, fluorescence and antioxidant properties of a binuclear Ag(I) complex based on the SPPh3 ligand

“…[9][10][11] The Ag(I) ion demonstrates linear, trigonal, square planar, square-pyramidal, trigonal-bipyramidal, tetrahedral, and octahedral coordination geometries with high affinity to both nitrogen and sulfur atoms. [12][13][14] Moreover, This ion is apt to form short Ag-Ag contacts as well as ligand unsupported interaction, which has been proved to be two of the most important factors contributing to the formation of such complexes and their special properties. [15][16] Furthermore, silver complexes show potential applications in photoluminescence, molecular recognition, and as antioxidant, antibacterial, and anticancer agents.…”