Thread-based microfluidic sensor for lithium monitoring in saliva

Lewińska, Izabela; Capitán-Vallvey, L.F.; Erenas, Miguel M.

doi:10.1016/j.talanta.2022.124094

Cited by 9 publications

(11 citation statements)

References 43 publications

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“…Izabela et al probed the lithium ion concentration in saliva by a microfluidic wire-based device. The combination of extractant and porous media was used to effectively improve the sensitivity of lithium ion extraction and device [ 182 ].…”

Section: Microfluidic Devices Based On Porous Media For Biomedical An...mentioning

confidence: 99%

Porous Structural Microfluidic Device for Biomedical Diagnosis: A Review

et al. 2023

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Microfluidics has recently received more and more attention in applications such as biomedical, chemical and medicine. With the development of microelectronics technology as well as material science in recent years, microfluidic devices have made great progress. Porous structures as a discontinuous medium in which the special flow phenomena of fluids lead to their potential and special applications in microfluidics offer a unique way to develop completely new microfluidic chips. In this article, we firstly introduce the fabrication methods for porous structures of different materials. Then, the physical effects of microfluid flow in porous media and their related physical models are discussed. Finally, the state-of-the-art porous microfluidic chips and their applications in biomedicine are summarized, and we present the current problems and future directions in this field.

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Section: Microfluidic Devices Based On Porous Media For Biomedical An...mentioning

confidence: 99%

Porous Structural Microfluidic Device for Biomedical Diagnosis: A Review

et al. 2023

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“…Still, the number of studies is relatively small, and almost no bioinspired concepts have been used by relevant researchers, resulting in a considerable research gap. For example, if we can apply the multiscale hierarchical microgroove structure of superhydrophilic Sarracenia trichomes to thread‐based open microfluidics, it will undoubtedly have a positive impact on microfluidics transport speed in open space [ 176–177 ] ; If the inner wall of the VFD tube or jet feeds could be modified into superhydrophobicity or superhydrophilicity, the structure, properties, and production of the synthetic products would be affected differently, or the selectivity and success rate of the detection/diagnostic results would be increased. [ 178–180 ] These are just simple ideas, but with the future efforts of scientists, eventually, bioinspired superwetting open microfluidics will certainly be established as a subject with practical application value.…”

Section: Emerging Applicationsmentioning

confidence: 99%

Bioinspired Superwetting Open Microfluidics: From Concepts, Phenomena to Applications

et al. 2023

Adv Funct Materials

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Microfluidics and bioinspired superwetting materials, as two crucial branches of scientific research, are entering their golden age of development. As an emerging interdisciplinary subject of these two fields, bioinspired superwetting open microfluidics is triggering technological revolutions in many disciplines, including rapid medical diagnosis, biochemical analysis, liquid manipulation, 3D printing, etc. However, this new research area has yet to attract extensive attention. So, a timely review is necessary to organize the development process, summarize current achievements, and discuss the challenges or chances for the ongoing scientific trend. In this review, the evolution from closed to open microfluidics is combed first. Then, three typical bioinspired superwetting systems are introduced emphatically. Based on this, the bioinspired superwetting open microfluidics is divided into different categories according to the bionic objects as the focus of this study. Taking natural phenomena as the entry point, the research from the underlying mechanism to the application is systematically discussed and summarized. Several emerging applications are also mentioned. Finally, some views on major problems, existing challenges, and developing trends are briefly put forward in this field to guide future research.

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“…For instance, threads possess excellent wicking properties and flexibility, making them promising candidates for creating microfluidic circuits. [90,97] By using nanomaterial-blended conductive threads, these threads could be fabricated as physical and chemical sensors and further interconnected with electronic circuitry for signal readout, modulation, and wireless transmission. The thread-based sensors could offer a reliable way to detect very small changes in electrical potential, enabling the measurement of ion exchanges in living tissues.…”

Section: Open-channel Microfluidic Chipsmentioning

confidence: 99%

Molecular Separation by Using Active and Passive Microfluidic chip Designs: A Comprehensive Review

Ebrahimi,

Icoz,

Didarian

et al. 2023

Adv Materials Inter

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Separation and identification of molecules and biomolecules such as nucleic acids, proteins, and polysaccharides from complex fluids are known to be important due to unmet needs in various applications. Generally, many different separation techniques, including chromatography, electrophoresis, and magnetophoresis, have been developed to identify the target molecules precisely. However, these techniques are expensive and time consuming. “Lab‐on‐a‐chip” systems with low cost per device, quick analysis capabilities, and minimal sample consumption seem to be ideal candidates for separating particles, cells, blood samples, and molecules. From this perspective, different microfluidic‐based techniques have been extensively developed in the past two decades to separate samples with different origins. In this review, “lab‐on‐a‐chip” methods by passive, active, and hybrid approaches for the separation of biomolecules developed in the past decade are comprehensively discussed. Due to the wide variety in the field, it will be impossible to cover every facet of the subject. Therefore, this review paper covers passive and active methods generally used for biomolecule separation. Then, an investigation of the combined sophisticated methods is highlighted. The spotlight also will be shined on the elegance of separation successes in recent years, and the remainder of the article explores how these permit the development of novel techniques.

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Thread-based microfluidic sensor for lithium monitoring in saliva

Cited by 9 publications

References 43 publications

Porous Structural Microfluidic Device for Biomedical Diagnosis: A Review

Porous Structural Microfluidic Device for Biomedical Diagnosis: A Review

Bioinspired Superwetting Open Microfluidics: From Concepts, Phenomena to Applications

Molecular Separation by Using Active and Passive Microfluidic chip Designs: A Comprehensive Review

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