Thr92Ala-DIO2 heterozygosity is associated with skeletal muscle mass and myosteatosis in patients with COVID-19
Fabyan Esberard de Lima Beltrão,
Daniele Carvalhal de Almeida Beltrão,
Giulia Carvalhal
et al.
Abstract:Introduction: The type 2 deiodinase and its Thr92Ala-DIO2 polymorphism have been linked to clinical outcomes in acute lung injury and COVID-19.
Objective: To identify a potential association between Thr92Ala-DIO2 polymorphism and body composition (appendicular muscle mass, myosteatosis, and fat distribution) and to determine whether they reflect the severity or mortality associated with the disease.
Methods: In this prospective cohort study (June-August 2020), 181 patients hospitalized with moderate-to-sever… Show more
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