Thoracolumbar Intervertebral Disc Area Morphometry in Elderly Chinese Men and Women

Wáng, Jùn-Qīng; Káplár, Zoltán; Deng, Min; Griffith, James F.; Leung, Jason C. S.; Kwok, Anthony; Kwok, Timothy; Leung, Ping Chung; Wáng, Yì Xiáng J.

doi:10.1097/brs.0000000000002482

Cited by 17 publications

(7 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On the other hand, for the vertebral bodies, lower BMD was associated with a decrease of vertebral anterior/middle/ posterior height, but not vertebral anterior-posterior diameter; lower BMD was associated with a decrease in vertebral volume, and an increased biconcavity index (15). Our 4-year longitudinal follow-up study with radiographs shows osteopenia and osteoporosis are associated with faster disc area decrease in both thoracic spine and lumbar spine, and both for both males and females (24). We can naturally assume that a decreased disc volume (as measured with MRI) and decreased disc lateral area (as measured with radiograph) are biomarkers of disc degeneration.…”

mentioning

confidence: 87%

Senile osteoporosis is associated with disc degeneration

Wáng

2018

Quant. Imaging Med. Surg.

Self Cite

View full text Add to dashboard Cite

mentioning

confidence: 87%

Senile osteoporosis is associated with disc degeneration

Wáng

2018

Quant. Imaging Med. Surg.

Self Cite

View full text Add to dashboard Cite

“…However, such grading is subjective and difficult to use for epidemiological studies. We developed a Disc Area Index for Lumbar spine (DAIL) index, which quantitatively classifies lumbar disc space into normal disc height or DSN (3). DAIL for each intervertebral level is calculated using Eq.…”

Section: Osteoporosis Is Positively Associated With Intervertebral Disc Degenerationmentioning

confidence: 99%

‘Healthier Chinese spine’: an update of osteoporotic fractures in men (MrOS) and in women (MsOS) Hong Kong spine radiograph studies

Wáng¹,

Deng²,

Griffith³

et al. 2022

Quant Imaging Med Surg

Self Cite

View full text Add to dashboard Cite

For the MrOS (Hong Kong) and MsOS (Hong Kong) baseline (BL) studies, community-dwelling 2,000 Chinese men (mean age: 72.3 years) and 2,000 Chinese women (mean age: 72.5 years) were recruited from 2001 to 2003. These two studies have spanned two decades till now. This review summarizes our spine radiograph results. Senile and post-menopausal osteoporosis were associated with intervertebral disc volume reduction; and in women, menopause accelerates disc degeneration. Elderly women's osteoporotic vertebral fracture (OVF) prevalence was double of that of elderly men. For year-4 follow-up (FU), male participants with BL OVF had little increased risk for further OVF. In our study comparing OVF rates in age-matched Hong Kong Chinese women and Italian Caucasian women (mean age: 74.1 years), endplate and/or cortex fracture (ECF) prevalence was 26% for Chinese and 47% for Italian. OVF with ≥40% vertebral height loss was recorded among 9.5% of the Chinese subjects while among 26% of the Italian subjects. OVFs in Italian subjects were more likely to be multiple and generally severer. Clinical spine fractures were recorded 133 cases/100,000 person-years in MrOS (Hong Kong) participants and 273 cases/100,000 person-years in MsOS (Hong Kong) participants. Literature review suggests the clinical vertebral fracture rates among elderly Hong Kong Chinese subjects are approximately half of those of American, Australian, and Canadian subjects. Data synthesis suggests elderly Caucasians have a higher degenerative spondylolisthesis prevalence, being approximately 70% higher than that of elderly Hong Kong Chinese. Literature review of other authors' publications shows, compared with Caucasians, Chinese have a much lower incident rate of back pain. We conclude that elderly Chinese have a generally healthier spine relative to elderly Caucasians.

show abstract

“…The relationship between LBP and woman gender has been shown in various studies (Troussier et al, 1999[ 36 ]; Schneider et al, 2006[ 34 ]; Bejia et al, 2005[ 6 ]; Wáng et al, 2016[ 38 ]; Yang et al, 2016[ 40 ]). Wáng et al (2018[ 37 ]) indicated that among all age groups, the prevalence of LBP is higher in women compared with men (Wáng et al, 2018[ 37 ]). Similarly, this developed scale is able to differentiate these two groups by giving higher scores of women.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, this developed scale is able to differentiate these two groups by giving higher scores of women. Wáng et al also identified the psychological factors as one of the possible causes for the higher prevalence of LBP in women compared with men (Wáng et al, 2018[ 37 ]). In this study, it was the psychosocial sub-scale that revealed the difference in prevalence of LBP between women and men.…”

Section: Discussionmentioning

confidence: 99%