Thoracic mesenchymoma of infancy

Respiratory insufficiency in a newborn with mesenchymal hamartoma of the chest wall occupying the thoracic cavity

“…These lesions were reported to show an initial period of rapid growth, as observed in the present case between the 28th and the 36th gestational weeks, which was followed by discontinuity of tumor enlargement or occasionally spontaneous regression [5]. With increased knowledge of the natural history of the disease, conservative management was often suggested [5,13]. On the other hand, urgent surgical resections were essential for infants whose lesions caused irreversible impairment to other organs, such as cardiovascular compression, respiratory distress, or neurologic disorders because of involvement of thoracic vertebrae.…”

Chest wall mesenchymal hamartoma associated with a massive fetal pleural effusion: a case report

“…Freeburn and McAloon [5] described the expectant management and long-term follow-up of a case of uncomplicated spontaneous resolution and rib remodeling and recommended a nonsurgical approach to the management of asymptomatic patients. Surgical intervention is indicated only to relieve cardiac or pulmonary symptoms or to facilitate chest reconstruction [1][2][3]. To our knowledge, our patient is the first case associated with a massive fetal pleural effusion and to undergo a pleuroamniotic shunt.…”

“…Surgical indications include cardiac or pulmonary compromise caused by compression or physically deforming masses [1][2][3]. We describe an extremely rare case associated with a massive pleural effusion detected in utero.…”

Mesenchymal (chondromatous) hamartoma of chest wall in a neonate: A case report and review of literature

“…17 The various histopathological of MHCW are described by many authors. 11,18,19 These are highly cellular small IJBAR (2013) 04 (12) www.ssjournals.com round, oval or spindle mesenchymal cells and fragments of hyaline cartilages with blood filled cavities. Immunohistochemical staining may demonstrates presence of S-100 protein in cartilaginous areas 11 .…”