Thoracic Manifestation of Granulomatosis with Polyangiitis: A Case Report

Rationale: Granulomatosis with polyangiitis (GPA) mostly affects the upper and lower respiratory tracts and the kidneys. Although it may also affect other systems, multiorgan damage to the upper respiratory tract, lungs, kidneys, skin, hearing, and vision is rare. Patient concerns: A 52-year-old man was admitted to our hospital with fever, epistaxis, anosmia, blood in sputum, proteinuria, limb rashes, hearing loss, diplopia, night sweats, and chest pain. The patient had no history of any illness. Diagnoses: GPA was established based on multisystem clinical manifestations, nasal tissue biopsy, and positive serum antibodies. Interventions: Medical treatment with glucocorticoid and immunosuppressants was given to the patient. Outcomes: The patient’s condition improved; computed tomography scan of the lung indicated shrinkage of the lesion, and there were no complications or recurrence within the 5-month follow-up period. Lessons: For GPA patients with multisystem involvement, detailed physical examination is required to improve the survival rate and prognosis.

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Granulomatosis with polyangiitis presenting with multisystem impairment

Li¹,

Zhao

Wang³

2022

Medicine: Case Reports and Study Protocols

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Thoracic Manifestation of Granulomatosis with Polyangiitis: A Case Report

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Granulomatosis with polyangiitis presenting with multisystem impairment

Granulomatosis with polyangiitis presenting with multisystem impairment

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