Thirty-day outcome and quality of life after endovascular abdominal aortic aneurysm repair in octogenarians based on the Endurant Stent Graft Natural Selection Global Postmarket Registry (ENGAGE)

Pol, Robert A.; Zeebregts, Clark J.; Sterkenburg, Steven M.M. van; Reijnen, Michel M.P.J.

doi:10.1016/j.jvs.2011.12.080

Cited by 39 publications

(27 citation statements)

References 28 publications

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“…The elderly population had a higher peri-operative rate of pulmonary complications (5.1% vs. 1%, P = 0.003) and access-site haematomas (12% vs. 2.4%, P = 0.001) with no difference in stroke, myocardial infarction, death, or ischaemic complications. Pol et al [17] analysed 274 patients from the Endurant Stent Graft Natural Selection Global Postmarket Registry (ENGAGE) vs. 926 younger patients using the EuroQoL-5 Dimensions Quality of Life (QoL) questionnaire. All-cause mortality and major adverse event rate peri-operatively was similar among groups ( P = 0.835 and P = 0.186, respectively).…”

Section: Results Following Evar In the Geriatric Populationmentioning

confidence: 99%

Endovascular abdominal aortic aneurysm repair in the geriatric population

Saratzis¹,

Mohamed²

2012

Journal of Geriatric Cardiology

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Abdominal aortic aneurysm (AAA) is a relatively common pathology among the elderly. More people above the age of 80 will have to undergo treatment of an AAA in the future. This review aims to summarize the literature focusing on endovascular repair of AAA in the geriatric population. A systematic review of the literature was performed, including results from endovascular abdominal aortic aneurysm repair (EVAR) registries and studies comparing open repair and EVAR in those above the age of 80. A total of 15 studies were identified. EVAR in this population is efficient with a success rate exceeding 90% in all cases, and safe, with early mortality and morbidity being superior among patients undergoing EVAR against open repair. Late survival can be as high as 95% after 5 years. Aneurysm-related death over long-term follow-up was low after EVAR, ranging from 0 to 3.4%. Endovascular repair can be offered safely in the geriatric population and seems to compare favourably with open repair in all studies in the literature to date.

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Section: Results Following Evar In the Geriatric Populationmentioning

confidence: 99%

Endovascular abdominal aortic aneurysm repair in the geriatric population

Saratzis¹,

Mohamed²

2012

Journal of Geriatric Cardiology

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“…This study does not report about the quality of life after operative or conservative treatment of an AAA. Earlier, the EVAR 1 and 2 and the DREAM trial reported conflicting results on outcome of quality of life after EVAR and open repair [5,20,22,24]. They all reported decrease in quality of life after EVAR and open repair of AAAs.…”

Section: Discussionmentioning

confidence: 99%

Outcome of elective treatment of abdominal aortic aneurysm in elderly patients

Leur

Flu

et al. 2015

International Journal of Surgery

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“…Indeed, the increase in 30‐day case fatality of acute AAA events with age was much greater in absolute terms than the increase in case fatality owing to elective AAA repair. One quarter of elective AAA repairs in the UK are already performed in patients over the age of 80, with excellent functional outcomes in the vast majority . Second, our estimates of effectiveness of screening took into account the shorter life expectancy in older individuals with known aneurysmal disease.…”

Section: Discussionmentioning

confidence: 99%

Population‐Based Study of Incidence of Acute Abdominal Aortic Aneurysms With Projected Impact of Screening Strategy

Howard

Banerjee

Fairhead

et al. 2015

JAHA

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BackgroundCurrent abdominal aortic aneurysm (AAA) screening in men age 65 might have limited impact on overall AAA death rates if incidence is moving to older ages. Up-to-date population-based studies of age-specific incidence, risk factors, and outcome of acute AAA are needed to inform screening policy.Methods and ResultsIn a prospective, population-based study (Oxfordshire, UK, 2002–2014), the incidence and outcome of acute AAA events were determined. Based on population projections and current incidence trends, the impact of screening strategies in the UK was estimated. Over the 12-year period, 103 incident acute AAA events occurred in the study population of 92 728. Incidence/100 000/year was 55 in men ages 65 to 74 years, but increased to 112 at 75 to 85 and 298 at ≥85, with 66.0% of all events occurring at age ≥75 years. Incidence at ages 65 to 74 was highest in male smokers (274), with 96.4% of events in men <75 years occurring in ever-smokers. Extrapolating rates to the UK population, using trial evidence of screening efficacy, the current UK screening program would prevent 5.6% of aneurysm-related deaths (315 200 scans/year: 1426/death prevented, 121/year-of-life saved). Screening only male smokers age 65 and then all men at age 75 would prevent 21.1% of deaths (247 900 scans/year; 297/death prevented, 34/year-of-life saved). By 2030, 91.0% of deaths will occur at age ≥75, 61.6% at ≥85, and 28.6% in women.ConclusionsGiven that two thirds of acute AAA occurred at ≥75 years of age, screening older age groups should be considered. Screening nonsmokers at age 65 is likely to have very little impact on AAA event rates.

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Thirty-day outcome and quality of life after endovascular abdominal aortic aneurysm repair in octogenarians based on the Endurant Stent Graft Natural Selection Global Postmarket Registry (ENGAGE)

Cited by 39 publications

References 28 publications

Endovascular abdominal aortic aneurysm repair in the geriatric population

Endovascular abdominal aortic aneurysm repair in the geriatric population

Outcome of elective treatment of abdominal aortic aneurysm in elderly patients

Population‐Based Study of Incidence of Acute Abdominal Aortic Aneurysms With Projected Impact of Screening Strategy

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