Thirteenth International Workshop on Electrogastrography
 Feinberg Pavillion
 Northwestern University Medical Center, Chicago, Illinois
 May 18‐19, 2005

Abstract

Gastric electrical stimulation (GES) using single channel has been under investigation for its therapeutic potential for gastroparesis. The aim of this study was to study the efficacy and efficiency of multi-channel GES in accelerating gastric emptying in dogs. The study was performed in eight dogs, and gastric emptying of liquid was assessed in three randomized sessions of control, one-channel GES and four-channel GES. It was found that (i) GES of both one-channel and four-channel was able to completely entrain the slow waves in the entire stomach. However, the stimulation energy required by four-channel GES was only 1% of that required by one-channel GES. (ii) Four-channel, but not one-channel, GES significantly and substantially accelerated gastric emptying. An increase of 121.0 and 93.9% was noted with four-channel GES at 30 and 60 min after the meal, respectively. It was concluded that four-channel GES is substantially more efficient and effective than conventional single-channel GES in improving gastric emptying. It is worthy to explore its therapeutic potential for gastroparesis in clinical settings.

Effects and Mechanisms of Electrical Stimulation of the Stomach, Duodenum, Ileum, and Colon on Gastric Tone in Dogs

“…Nine healthy female hound dogs (14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) were used in the study. After an overnight fast, a surgical procedure was performed on each dog under anesthesia.…”

Surgical treatment of medically refractory gastroparesis in the morbidly obese

“…Previous studies have reported a beneficial effect on symptoms, overall quality of life, and nutritional status from GES implantation [1,9,27]. In this study, GES implantation was offered to medically refractory gastroparesis patients as the primary surgical option since there is limited published data on the safety and efficacy of RYGJ for gastroparesis.…”

Effects and Mechanisms of Vaginal Electrical Stimulation on Rectal Tone and Anal Sphincter Pressure

“…However, VES may be more applicable than anal electrical stimulation in patients with fecal incontinence because the patients with fecal incontinence typically have weak anal sphincters, which may not be able to hold the stimulation catheter well. A number of previous studies with gastric or intestinal electrical stimulation showed that electrical stimulation with short pulses or trains of short pulses was ineffective in altering gastric or intestinal motility, 31,32 whereas electrical stimulation with long pulses or trains of long pulses was capable of entraining gastric or intestinal slow waves, 31,[33][34][35] altering gastric or intestinal contraction, [36][37][38] and accelerating or delaying gastric emptying. 31,33 Therefore, electrical stimulation with long pulses or trains of long pulses was selected as stimulation methods in this study.…”