Thiourea-Cu(OTf)₂/NIS-synergistically promoted stereoselective glycoside formation with 2-azidoselenoglycosides or thioglycosides as donors

Abstract

NIS with a catalytic amount of thiourea and Cu(OTf) composes a powerful activator system for 2-azidoselenoglycoside and thioglycoside donors, allowing stereoselective glycosylation of alcoholic receptors to furnish the expected glycosides.