Thiosemicarbazones-Loaded Injectable Hydrogels with Self-Healing and Antibacterial Activity for Wound Healing
Peifang Wang,
Yue Su,
Min Ma
et al.
Abstract:An injectable hydrogel loading α-N-heterocyclic thiosemicarbazones with antibacterial activity was designed to attain therapy against wounds with high efficiency. In the present study, the injectable FPZ-H 2 L hydrogel was synthesized by loading 2,6-diacetylpyridine bis(N 4 -methylthiosemicarbazone) (H 2 L) on transition-metal ions (Zn 2+ )-cross-linked-folic acid (FA)-co-polydopamine (PDA) hydrogel (FPZ hydrogel). The injectable hydrogel (FPZ-H 2 L) cross-linked by coordination and hydrogen bonds displayed an… Show more
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