Thiol containing carboxylic acids remove the CTAB surfactant onto the surface of gold nanorods: An FTIR spectroscopic study

Garabagiu, Sorina; Bratu, Ioan

doi:10.1016/j.apsusc.2013.08.006

Cited by 20 publications

(14 citation statements)

References 23 publications

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“…Centrifugation-washing method is the basic and commonly used route to remove CTAB on the surface of GNRs [ 38 – 41 ]. This method removes the excess CTAB on the surface of GNRs by centrifuging GNRs solution and washing GNRs with deionized (DI) water.…”

Section: Toxicity Reduction Of Gnrsmentioning

confidence: 99%

“…As described in phase transfer method section [ 42 – 44 ], thiol-containing carboxylic acids are often utilized to be conjugated with GNRs. Garabagiu et al [ 41 ] reported that the GNRs solution was centrifuged 3 times at 10,000 rpm to remove the CTAB and then employed 3-mercaptopropionic acid (MPA) for further surface functionalization of GNRs. Dai et al [ 50 ] utilized a place exchange reaction (carried out inside an ionic exchange resin) between CTAB-capped GNRs and MUA to replace CTAB by MUA.…”

Section: Toxicity Reduction Of Gnrsmentioning

confidence: 99%

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Preparation, toxicity reduction and radiation therapy application of gold nanorods

et al. 2021

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Gold nanorods (GNRs) have a broad application prospect in biomedical fields because of their unique properties and controllable surface modification. The element aurum (Au) with high atomic number (high-Z) render GNRs ideal radiosensitive materials for radiation therapy and computed tomography (CT) imaging. Besides, GNRs have the capability of efficiently converting light energy to heat in the near-infrared (NIR) region for photothermal therapy. Although there are more and more researches on GNRs for radiation therapy, how to improve their biocompatibility and how to efficiently utilize them for radiation therapy should be further studied. This review will focuse on the research progress regarding the preparation and toxicity reduction of GNRs, as well as GNRs-mediated radiation therapy. Graphical Abstract

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Section: Toxicity Reduction Of Gnrsmentioning

confidence: 99%

Section: Toxicity Reduction Of Gnrsmentioning

confidence: 99%

Preparation, toxicity reduction and radiation therapy application of gold nanorods

et al. 2021

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“…Particularly interesting for thiol determination are simple, inexpensive, robust, and fast methods which can be used for many different molecular and nanoscale systems. Methods used so far include elemental analysis, , inductively coupled plasma optical emission spectroscopy (ICP-OES) and mass spectrometry (ICP-MS), thermogravimetric analysis (TA), , liquid chromatography with tandem mass spectrometry (LC-MS/MS, HPLC-MS/MS), , electrospray ionization mass spectrometry (ESI-MS), electrochemical methods, , surface-enhanced Raman spectroscopy (SERS), Fourier transform infrared (FTIR) spectroscopy , as well as photometric and fluorometric assays. , The sensitivity of TA and ICP-OES (for light elements like sulfur) is rather low (i.e., in the ppm range), thus requiring relatively large amounts of material. Moreover, these methods as well as MS-based techniques need comparatively expensive instrumentation, considerable expertise, and can be time-consuming.…”

mentioning

confidence: 99%

Ellman’s and Aldrithiol Assay as Versatile and Complementary Tools for the Quantification of Thiol Groups and Ligands on Nanomaterials

et al. 2016

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Simple, fast, and versatile methods for the quantification of thiol groups are of considerable interest not only for protein analysis but also for the characterization of the surface chemistry of nanomaterials stabilized with thiol ligands or bearing thiol groups for the subsequent (bio-) functionalization via maleimide-thiol chemistry. Here, we compare two simple colorimetric assays, the widely used Ellman's assay performed at alkaline pH and the aldrithiol assay executed at acidic and neutral pH, with respect to their potential for the quantification of thiol groups and thiol ligands on different types of nanoparticles like polystyrene nanoparticles, semiconductor nanocrystals (SC NC), and noble metal particles, and we derive criteria for their use. In order to assess the underlying reaction mechanisms and to obtain stoichiometry factors mandatory for reliable thiol quantification, both methods were studied photometrically and with electrospray ionization time-of-flight mass spectrometry (ESI-TOF-MS), thereby demonstrating the influence of different thiols on the reaction mechanism. Our results underline the suitability of both methods for the quantification of directly accessible thiol groups or ligands on the surface of 2D- and 3D-supports, here exemplarily polystyrene nanoparticles. Moreover, we could derive strategies for the use of these simple assays for the determination of masked (i.e., not directly accessible) thiol groups like disulfides such as lipoic acid and thiol stabilizing ligands coordinatively bound to Cd and/or Hg surface atoms of II/VI and ternary SC NC and to gold and silver nanoparticles.

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“…In their study, Garabagiu et al 13 reported the ligand exchange reaction with 3-mercaptopropionic acid (Fig. 5b).…”

Section: Organic Moleculesmentioning

confidence: 91%

Surface modifications of gold nanorods for applications in nanomedicine

2015

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Thiol containing carboxylic acids remove the CTAB surfactant onto the surface of gold nanorods: An FTIR spectroscopic study

Cited by 20 publications

References 23 publications

Preparation, toxicity reduction and radiation therapy application of gold nanorods

Preparation, toxicity reduction and radiation therapy application of gold nanorods

Ellman’s and Aldrithiol Assay as Versatile and Complementary Tools for the Quantification of Thiol Groups and Ligands on Nanomaterials

Surface modifications of gold nanorods for applications in nanomedicine

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