Thin-Layer Cytology Findings of Papillary Adenosquamous Carcinoma of the Cervix

Ng, Wai-Kuen

doi:10.1159/000326583

Cited by 10 publications

(4 citation statements)

References 25 publications

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“…It is possible to diagnose a superficial lesion based on histological findings, even if invasion and atypia are modest, on biopsy 1 . In PSTCC of the uterine cervix, high‐grade squamous intraepithelial lesions (HSILs) with bland‐looking basal cells may contribute to underdiagnosis due to the scarce of malignant cells 6–8 . Therefore, accurate reconnaissance of clinical cytological features is needed for the diagnosis and staging of PSTCC.…”

Section: Discussionmentioning

confidence: 99%

“… 1 In PSTCC of the uterine cervix, high‐grade squamous intraepithelial lesions (HSILs) with bland‐looking basal cells may contribute to underdiagnosis due to the scarce of malignant cells. 6 , 7 , 8 Therefore, accurate reconnaissance of clinical cytological features is needed for the diagnosis and staging of PSTCC. Moreover, in histopathological specimens, as a result of PSTCC's complex papillary structure, it is challenging to detect stromal invasion without deep biopsies.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Papillary squamotransitional cell carcinoma of the uterine cervix: A rare case report

Arab

Pirastehfar

Moghaddam

et al. 2023

Clinical Case Reports

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Papillary squamotransitional cell carcinoma of the uterine cervix: A rare case report

Arab

Pirastehfar

Moghaddam

et al. 2023

Clinical Case Reports

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“…PSTCC of the uterine cervix is an extremely rare entity, and the presence of bland-looking basaloid cells or high grade squamous intraepithelial lesions (HSILs), together with scantiness of malignant cells, may lead to underdiagnosis of these histopathological variants [ 1 , 9 , 10 ]. Thus the identification of the subtle cytological characteristics with clinical correlation is mandatory to conclude diagnostic and staging dilemma.…”

Section: Discussionmentioning

confidence: 99%

Papillary Squamotransitional Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature

Akbar

Tunio

Al-Dandan

et al. 2016

Case Reports in Obstetrics and Gynecology

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Introduction. Papillary squamotransitional cell carcinoma (PSTCC) is an uncommon histopathological variant of squamous cell carcinoma (SCC) of the uterine cervix, which occurs in postmenopausal women. Presentation of Case. Herein, we describe a case of a 63-year-old woman who presented with 4-month history of postmenopausal vaginal bleeding. Vaginal examination revealed a fragile lesion of size 1 × 1 cm invading left posterior vaginal fornice and parametrium. Biopsy showed the presence of papillae containing fibrovascular cores lined by multilayered atypical epithelial cells resembling squamous and transitional cell epithelium, confirming the diagnosis of PSTCC of the uterine cervix. After staging work-up she was staged according to the International Federation of Gynecology and Obstetrics (FIGO) staging system 2009 as FIGO IIB, and she was started on extended field concurrent chemoradiation. Discussion. PSTCC of the uterine cervix is an extremely rare and aggressive entity. PSTCC is often characterized by the presence of papillary structures with prominent fibrovascular cores. PSTCC of the uterine cervix should be differentiated from transitional cell carcinoma, squamous papilloma, papillary adenocarcinoma, and cervical intraepithelial neoplasia with papillary features. Conclusion. PSTCC of the uterine cervix is a diagnostic challenge; further studies regarding the mechanism underlying the development of PSCC are warranted.

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“…Las fi guras mitóticas son comunes, los nucléolos prominentes y es también posible visualizar ocasionales células disqueratóticas. En el otro lado del espectro se pueden reconocer células con apariencia blanda que recuerdan la metaplasia escamosa o elementos con citomorfología que sugiere lesión intraepitelial de alto grado, con cromatina gruesa y núcleo irregular (29,38). Estas células cuando no están agrupadas formando papilas, están aisladas o dispuestas en conglomerados de multicapas o grupos pequeños a manera de sincitio.…”

Section: Discussionunclassified

Carcinoma Papilar De Células Escamotransicionales Del Cérvix: Presentación De 16 Casos Y Revisión De La Literatura

Patiño³

et al. 2009

Rev. chil. obstet. ginecol.

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RESUMENEl carcinoma papilar de células escamotransicionales del cuello uterino, es una variante rara del carcinoma escamoso, que se caracteriza por presentar un patrón arquitectural papilar, por ser profundamente invasivo y por su tendencia a recidivar y metastatizar tardíamente. Se presenta una serie de 16 casos y se analizan los hallazgos clínicos, macroscópicos, histopatológicos, citológicos e inmuno-histoquímicos. Se revisa la literatura, discutiendo la posible génesis de este proceso neoplásico. PALABRAS CLAVE: Carcinoma escamotransicional, carcinoma papilar escamoso SUMMARYPapillary squamous-transitional cell carcinoma of the uterine cervix is a rare variant of squamous cell carcinoma. It is characterized by their papilar architectural pattern, to be deeply invasive, and their tendency to show a late metastasize and local recurrence. A series of 16 cases is presented and their clinical, macroscopic, histopathological, cytologic and immunohistochemical fi ndings are analyzed. The literature is reviewed and the possible genesis of this neoplasm is discussed. KEY WORDS: Squamotransitional carcinoma, papillary squamous carcinoma INTRODUCCIÓNEl cáncer de cuello uterino fue y continua siendo actualmente un factor preponderante de morbimortalidad a nivel mundial, constituyendo una de las principales causas de muerte entre las mujeres en todo el mundo. La mayor incidencia y mortalidad se presenta en países en vía de desarrollo, alcanzando en América Latina y el Caribe cerca de 37.600 decesos anuales (1). Es evidente que este proceso representa un problema relevante de salud públi-ca en Latinoamérica, pudiéndose prevenir y curar cuando se realiza una detección precoz y oportuna de sus lesiones precursoras o del mismo cáncer, de ahí la importancia de un buen diagnostico, tratamiento y seguimiento (2).

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Thin-Layer Cytology Findings of Papillary Adenosquamous Carcinoma of the Cervix

Cited by 10 publications

References 25 publications

Papillary squamotransitional cell carcinoma of the uterine cervix: A rare case report

Papillary squamotransitional cell carcinoma of the uterine cervix: A rare case report

Papillary Squamotransitional Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature

Carcinoma Papilar De Células Escamotransicionales Del Cérvix: Presentación De 16 Casos Y Revisión De La Literatura

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