Thin-layer chromatography coupled with high performance liquid chromatography for determining tetrabromobisphenol A/S and their derivatives in soils

Abstract

As brominated flame retardants (BFRs), tetrabromobisphenol A/S (TBBPA/S) and their derivatives have raised wide concerns owing to their widely usage, distributions and adverse effects on human health, thus monitoring these BFRs was urgently needed. In this study, a rapid and cost-effective method based on thin-layer chromatography (TLC) sample pre-treatment coupled with high performance liquid chromatography-diode array detector (HPLC-DAD) (UV=214nm) was developed for determining TBBPA/S and their derivatives in soils, including TBBPA, TBBPA bis(allyl ether) (TBBPA-BAE), TBBPA bis(2,3-dibromopropyl ether) (TBBPA-BDBPE), TBBPS bis(allyl ether) (TBBPS-BAE) and TBBPS bis(2,3-dibromopropyl ether) (TBBPS-BDBPE). The method detection limits (MDLs) and the method quantification limits (MQLs) for these BFRs ranged from 0.023 to 0.087μggdw and 0.076-0.29μggdw, respectively. The recoveries were 41-108% and both RSD of repeatability and intermediate precision were less than 11%. The developed method presented good performance for analyzing natural soil samples collected from BFRs industrial park, suggesting its great application potential for monitoring environmental TBBPA/S and their derivatives.

Detection of Frequently Used Pesticides in Apple Orchard Soil in China by High Resolution Mass Spectrometry

“…Correspondingly, matrix-matched standard solutions were prepared (50, 500 ng/mL) by mixing the corresponding standards with concentrated sample extracts. The matrix-induced signal suppression or enhancement was determined by comparison with the signals of pure standards [22]. The LODs and LOQs were established based on the lowest concentration with a signal-to-noise ratio (S/N) of 3:1 and 10:1.…”

New Mixed Bromine/Chlorine Transformation Products of Tetrabromobisphenol A: Synthesis and Identification in Dust Samples from an E-Waste Dismantling Site

“…Studies have also indicated that an etherified group at a position in the phenolic rings of TBBPA is crucial for the chemically induced adipogenic effects . Furthermore, several analogues of TBBPA, such as tetrabromobisphenol S bis­(2,3-dibromopropyl ether) and TBBPA bis­(2,3-dibromopropyl ether), have been introduced into markets. , These analogues may be released into the environment during the lifetime of products, and thus may widely occur in the environment and biota together with their transformation products. , …”

Endocrine disrupting chemicals in water and recent advances on their detection using electrochemical biosensors

“…TBBPA, TBBPS and TCBPA known as common brominated flame retardants, they are also often used in plastic paints, synthetic textiles, and electrical devices. 22,23 most hazardous and anti-estrogen chemicals, consisting of PCB77 and other 11 congeners. 24 Moreover, non-dioxin-like PCBs like PCB28, PCB101, and PCB180 are also frequently reported.…”

“…TBBPA, TBBPS and TCBPA are known as common brominated flame retardants, and they are also often used in plastic paints, synthetic textiles, and electrical devices. 22,23…”