Adhesive capsulitis (AC) is a painful and disabling disorder, which caused restricted motion and chronic pain of shoulder. Intracavitary contrast-enhanced ultrasound has been recently applied to assess obstructive bile duct diseases, tubal patency, vesicoureteric reflux and so on. The aim of this study was to detect the value of US-arthrography by injecting the contrast agent SonoVue into glenohumeral joint compared with US in diagnosing AC. Utrasound (US) and US-arthrography images of 45 patients with AC were compared with that of 45 control subjects without AC with MRI as a gold standard. Patients with AC had a significantly thickened coracohumeral ligment (CHL, 3.1 mm) and inferior capsule (3.5 mm) on US, and a decreased volume of axillary recess (1.14 ml) on US-arthrography compared with the control subjects (1.59 ml). Filling defect (91.1%) and synovitis-like abnormality (75.6%) in the joint on US-arthrography were more sensitive than that of rotator interval abnormality (71.1%), thickened CHL more than 3 mm (64.4%), thickened inferior capsule more than 3.5 mm (66.7%) on US respectively for diagnosis of AC. Consequently, US-arthrography was more effective method than US for assessment of AC. Filling defects of joint cavity and synovitis-like abnormality in the joint are characteristic USarthrography findings for diagnosing AC.Adhesive capsulitis of the shoulder (AC), also known as frozen shoulder, is an inflammatory and fibrosing condition of the shoulder characterised by progressive pain and decreased range of motion of the glenohumeral joint 1, 2 . It is a said to be a self-limiting condition lasting for an average of 2-3 years, but up to 40% of patients may have persistent symptoms and restricted movement beyond 3 years, with 15% left with permanent disability 3, 4 . The etiology is still unknown, which may be associated with diabetes mellitus, Dupuytren disease, shoulder trauma, various cardiac, endocrine, and neurologic disorders 5,6 . Although AC is much less common than subacromial impingement syndrome, calcific tendinitis and rotator cuff tear, it is difficult to differentiate them from each other based on clinical presentation sometimes. So it is of great importance to explore some characteristic imaging findings of AC in order to make an accurate diagnosis and choose the treatment further.Arthrography, ultrasound (US), plain magnetic resonance imaging (MRI) and MR arthrography (MRA) may provide reliable imaging indicators of frozen shoulder 7 . The traditional shoulder arthrography was used to assess the volume of the glenohumeral joint. Both US and MRI have high soft-tissue resolution and are widely used to assess coracohumeral ligament (CHL) and capsule and synovium for AC [8][9][10] . Numerous specific MRI/MRA findings have been reported to diagnose AC, which includes thickening of the CHL, thickening of the joint capsule in the rotator cuff interval and axillary recess, effacement of the axillary recess, obliteration of subcoracoid fat triangle and so on 7, 10-13 .Recently, contrast enhanced u...