Thiamine-functionalized silver–copper bimetallic nanoparticles-based electrochemical sensor for sensitive detection of anti-inflammatory drug 4-aminoantipyrine

Saeed, Annum; Akhtar, Mehwish; Zulfiqar, Sonia; Hanif, Farzana; Alsafari, Ibrahim A.; Agboola, Philips O.; Haider, Sajjad; Warsi, Muhammad Farooq; Shakir, Imran

doi:10.1007/s11696-021-02042-7

Cited by 5 publications

(3 citation statements)

References 62 publications

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“…Bimetallic nanoparticles have been used in the fabrication of nanosensors, nanochips, nano semiconductors and nanocoating. For example, Ag-Cu, Au-Cu, Fe-Mn, Pd-Ru, Ag-Cu, Co-Ni, Au-Ag, Au-Pt, Cu-Sn and Pd-Au bimetallic nanoparticles have been used to fabricate sensors/biosensors that can sense dimethoate [34], hydrazine [30] and detect Salmonella typhimurium in milk samples [275], as well as an anti-cancer drug [276], anti-inflammatory drug 4-aminoantipyrine [277], luteolin [278], favipiravir [279], diclofenac [280], glucose in serum [281] and coal mine gases sensor [131]. For detecting pesticide contaminants in the environment, many bimetallic nanoparticles have been used including Ag-Au, Au-Pd, Au-Pt, Au-Ag for detecting organophosphorus pesticides, carbamates nerve agents, and pesticides of leachate in contaminated groundwater [282][283][284][285].…”

Section: Engineering Applicationmentioning

confidence: 99%

Synthesis of Bimetallic Nanoparticles and Applications—An Updated Review

Idris

Roy

2023

Crystals

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The manipulation of matter at the atomic level (nanotechnology) has experienced an explosion in research interest in recent years. Bimetallic nanoparticles are vital due to their high biocompatibility, stability and comparatively less toxicity. The synthesis methods that include physical, chemical and biological methods are explored and explained in detail, along with their advantages. They have a wide range of applications due to their synergistic properties including biological applications (in medicine and agriculture), environmental application (in water treatment and removal of toxic contaminants), engineering application (in nanosensors, nanochips and nano-semiconductors) and chemical and physical application (in optics, catalysis and paints). The green synthesis approach is a promising method of synthesis that can give rise to more biocompatible and less toxic bimetallic nanoparticles due to increasing environmental pollution. However, despite these interesting attributes of bimetallic nanoparticle, there is still much work to be done to improve the biocompatibility of bimetallic nanoparticles because of their toxicity and potentially hazardous effects.

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Section: Engineering Applicationmentioning

confidence: 99%

Synthesis of Bimetallic Nanoparticles and Applications—An Updated Review

Idris

Roy

2023

Crystals

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“…Thiamine demonstrates significant coordination with nanoparticles (NPs) in the presence of sulfur moieties. 10 Riboflavin (vitamin B2) is a biochemically active vitamin that is a member of the enormous flavin family and is a crucial cofactor in enzymatic reactions, including the Krebs cycle. The fluorescence and redox capabilities of riboflavin (RF) are due to the isoalloxazine ring group's presence in its chemical structure.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical sensing of B-complex vitamins: current challenges and future prospects with microfluidic integration

Pakeeza,

Draz,

Yaqub

et al. 2024

RSC Adv.

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“…Metallic/bimetallic nanoparticles have been shown to have antibacterial [27], anticancer [28], anti-inflammatory [29], and antioxidant properties [30]. The small size and large surface area of nanoparticles allow them to interact with cells and tissues [31].…”

Section: Introductionmentioning

confidence: 99%

Phytogenic Synthesis and Characterization of Silver Metallic/Bimetallic Nanoparticles Using Beta vulgaris L. Extract and Assessments of Their Potential Biological Activities

Elattar,

Ghoniem,

Al-Otibi

et al. 2023

Applied Sciences

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The synthesis of novel nanomedicines through eco-friendly protocols has been applied on a large scale with the prediction of discovering alternate therapies. The current work attained phytogenic synthesis of Ag-mNPs, AgSeO2-bmNPs, and Ag-TiO2-bmNPs through bio-reduction using an aqueous extract of Beta vulgaris (red beetroot). The phytochemical profile of the eco-friendly synthesized metallic/bimetallic nanoparticles was studied. The optical properties of nano-solutions were studied via UV-visible spectroscopy. The Fourier-transform infrared spectroscopy (FT-IR) spectral analyses revealed that stretching vibrations at wavenumbers 3303.81–3327.81 cm−1 attributed to phenolic hydroxyl groups documented shifts in the values in this range owing to proton dissociation through the bio-reduction of the metal ions. The surface morphology and the charge of the nanoparticles were investigated using a Transmission Electron Microscope (TEM) and zeta potential analyses. The prepared nano-solutions showed lower antioxidant activity (1,1-Diphenyl-2-picrylhydrazyl (DPPH•) and phosphomolybdate assays) than the plant extract. These results together with phytochemical analyses support the participation of the reactive species (phenolic contents) in the bio-reduction of the metal ions in the solutions through the formation of metallic/bimetallic nanoparticles. Ag-mNPs, AgSeO2-bmNPs, and Ag-TiO2-bmNPs showed antibacterial potentiality. AgSeO2-bmNPs were superior with inhibitory zone diameters of 34.7, 37.7, 11.7, and 32.7 mm against Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, and Salmonella enterica, respectively. Applying the Methylthiazole Tetrazolium (MTT) assay, the Ag-TiO2 bmNPs revealed potent cytotoxicity against the HePG2 tumor cell line (IC50 = 18.18 ± 1.5 µg/mL), while Ag-SeO2 bmNPs revealed the most potent cytotoxicity against the MCF-7 cell line (IC50 = 17.92 ± 1.4 µg/mL).

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Thiamine-functionalized silver–copper bimetallic nanoparticles-based electrochemical sensor for sensitive detection of anti-inflammatory drug 4-aminoantipyrine

Cited by 5 publications

References 62 publications

Synthesis of Bimetallic Nanoparticles and Applications—An Updated Review

Synthesis of Bimetallic Nanoparticles and Applications—An Updated Review

Electrochemical sensing of B-complex vitamins: current challenges and future prospects with microfluidic integration

Phytogenic Synthesis and Characterization of Silver Metallic/Bimetallic Nanoparticles Using Beta vulgaris L. Extract and Assessments of Their Potential Biological Activities

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