Abstract:IM Al-Fawaz, AS Al-Herbish, NAM Al-Jurayyan, AM Abo-Bakr, Thiamine Dependent Anemia in Didmoad (Wolfram) Syndrome: Further Studies and Report of Two Additional Cases. 1992; 12(3): 309-312 The DIDMOAD syndrome includes diabetes mellitus (DM) and optic atrophy (OA), variously associated with diabetes insipidus (DI), sensorineural deafness (D), dilatation of the urinary tract, and other minor abnormalities. Historically, the association of diabetes mellitus (DM) with optic atrophy (OA) was first described b… Show more
“…Initial reports claimed that thiamine supplementation decreased insulin requirement in these patients (92–94). However, this was due to the fact that patients with thiamine responsive anemia with DM and deafness had been mistaken for Wolfram syndrome.…”
“…Initial reports claimed that thiamine supplementation decreased insulin requirement in these patients (92–94). However, this was due to the fact that patients with thiamine responsive anemia with DM and deafness had been mistaken for Wolfram syndrome.…”
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